慢性乙肝患者焦虑和抑郁状况调查及相关因素分析

目的探讨慢性乙肝患者焦虑和抑郁状况及相关影响因素。方法选取2018年6月—2020年5月资阳市第四人民医院收治的慢性乙肝患者142例,进行汉密尔顿抑郁量表(hamilton depression scale,HAMD)、汉密尔顿焦虑量表(hamilton anxiety scale,HAMA)评估,并收集相关临床资料,分析焦虑和抑郁的发生情况及其影响因素。结果慢性乙肝患者焦虑和抑郁的患病率为26.06%和32.39%,焦虑和抑郁的共病率为13.38%。单因素分析结果显示,较高文化程度、管理者及有危险有害饮酒的患者焦虑患病率较高,差异均有统计学意义(P<0.05),独居、较高文化程度及一般文职人员的患者抑郁患病率较高,差异均有统计学意义(P <0.05)。多因素Logistic回归分析结果显示,管理者和危险有害饮酒是慢性乙肝患者焦虑的影响因素,危险有害饮酒是患者抑郁的影响因素。结论慢性乙肝患者焦虑抑郁的患病率较高,不同婚姻状况、职业、文化程度、饮酒情况及病程的患者焦虑抑郁程度具有差异,管理者职业和饮酒增加慢性乙肝患者发生焦虑的风险,饮酒增加发生抑郁的风险。

Survey on Mental Health in Patients With Chronic Hepatitis B and Analysis of its Related Factors

Objective To investigate the mental health in patients with chronic hepatitis B and analyze its related factors.Methods A total of 142 patients with chronic hepatitis B,who were treated in the Fourth People’s Hospital of Ziyang from June 2018 to May 2020,were enrolled in this study.HAMA and HAMD Scale were used to evaluate,the clinical characteristics were collected and recorded,the incidence of anxiety and depression and its influencing factors were analyzed.Results The prevalence of anxiety and depression in patients with chronic hepatitis B was 26.06% and 32.39%,respectively,and the rate of comorbidity of anxiety and depression was 13.38%.The results of univariate analysis showed that patients with higher educational level,managers and dangerous and harmful drinking had a higher prevalence of anxiety,and the difference was statistically significant(P<0.05).Patients living alone,with higher educational level and general civil servants had a higher prevalence of depression,and the difference was statistically significant(P<0.05).Multivariate Logistic regression analysis showed that managers and dangerous and harmful drinking were the influencing factors of anxiety in patients with chronic hepatitis B.dangerous and harmful drinking was the influencing factor of depression.Conclusion The prevalence of anxiety and depression are high in patients with chronic hepatitis B,the prevalence is different among marital,education,occupations,drinking and course of disease.Management worker and drinking increase the risk of anxiety,drinking increase the risk of depression.