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| 腔内影像学方法评价降脂治疗对冠状动脉粥样硬化斑块影响的研究进展 | |
| 引用本文： | 张爽,李之凡,钱杰,吴娜琼. 腔内影像学方法评价降脂治疗对冠状动脉粥样硬化斑块影响的研究进展[J]. 基础医学与临床, 2022, 42(3): 366-371. DOI: 10.3969/j.issn.1001-6325.2022.03.003 |
| 作者姓名： | 张爽 李之凡 钱杰 吴娜琼 |
| 作者单位： | 中国医学科学院阜外医院 国家心血管病中心 心血管代谢中心,北京100037 |
| 摘 要： | 动脉粥样硬化斑块与动脉粥样硬化性心血管疾病(atherosclerotic cardiovascular diseases,ASCVD)的发生及发展密切相关.借助腔内影像学,如血管内超声(intravascular ultrasound,IVUS)、光学相干成像(optical coherence tomography... |
| 关 键 词： | 腔内影像学 血管内超声 光学相干成像 近红外光谱成像 降胆固醇治疗 动脉粥样硬化斑块 |
Effects of lipid-lowering therapy on coronary atherosclerotic plaque evaluated by intravascular imaging |
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| ZHANG Shuang,LI Zhi-fan,QIAN Jie,WU Na-qiong. Effects of lipid-lowering therapy on coronary atherosclerotic plaque evaluated by intravascular imaging[J]. Basic Medical Sciences and Clinics, 2022, 42(3): 366-371. DOI: 10.3969/j.issn.1001-6325.2022.03.003 | |
| Authors: | ZHANG Shuang LI Zhi-fan QIAN Jie WU Na-qiong |
| Affiliation: | (Cardiometabolic Center, Fuwai Hospital, National Center for Cardiovascular Diseases & Chinese Academy of Medical Sciences, Beijing 100037,China) |
| Abstract: | The progression of atherosclerotic plaque is one of the most important causes of cardiovascular events in patients with atherosclerotic cardiovascular diseases(ASCVD).With the help of intravascular imaging,such as intravascular ultrasound(IVUS),optical coherence tomography(OCT)and near-infrared spectroscopy(NIRS),it is possible to show the details of the plaque morphological characteristics.Current research suggested that lipid-lowering drugs lead to plaque stabilization and regression mainly by reducing low-density lipoprotein cholesterol(LDL-C).This review focuses on the effects of lipid-lowering therapy on coronary atherosclerotic plaque evaluated by intravascular imaging. |
| Keywords: | intravascular imaging intravascular ultrasound(IVUS) optical coherence tomography(OCT) near-infrared spectroscopy(NIRS) lipid-lowing therapy atherosclerotic plaque |
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