TyG指数联合血管功能指标对冠状动脉狭窄程度的预测价值

目的:探讨甘油三酯葡萄糖乘积指数(TyG指数)、联合肱动脉血流介导的血管舒张(FMD)、踝肱指数(ABI)、臂踝脉搏波传导速度(baPWV)这3种血管功能相关指标对冠心病患者冠状动脉(冠脉)狭窄程度的预测价值.方法:回顾性纳入确诊为冠心病的患者200例,根据Gensini评分将患者分为低狭窄组(97例)和高狭窄组(10...

The value of TyG index combined with vascular function indexes in predicting the degree of coronary artery stenosis

Objective: To investigate the value of triglyceride glucose product index(TyG index), combined brachial artery flow-mediated vasodilation(FMD), ankle-brachial index(ABI) and brachial-ankle pulse wave velocity(baPWV) in predicting the degree of coronary artery stenosis in patients with coronary atherosclerotic heart disease. Methods: The 200 patients with coronary atherosclerotic heart disease were retrospectively enrolled. According to Gensini score, the patients were divided into low stenosis group and high stenosis group. The correlation between TyG index, FMD, ABI, baPWV and the degree of coronary artery stenosis was analyzed. The logistic regression model was constructed and the receiver operating characteristic(ROC) curve was drawn to evaluate the ability of TyG index and three vascular function related indexes in predicting the degree of coronary artery stenosis. Results: Among patients with coronary heart disease, the history of smoking, TyG index, FMD, ABI, baPWV, Hs-CRP were significantly increased in high coronary artery stenosis group than those in low coronary artery stenosis group. Logistic multivariate regression analysis showed that smoking, TyG index and baPWV were independent risk factors. The area under the ROC curve drawn by the combined coefficient of TyG index and baPWV was 0.705. Conclusion: TyG index is an independently risk factor in judging the degree of coronary artery stenosis of coronary heart disease. TyG index and baPWV can better predict the degree of coronary artery stenosis.