| 益气养心颗粒中丹参提取工艺的研究 |
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| 引用本文： | 闵建华,孟亚会,陈明民,章振鹏,孙亮,向飞军. 益气养心颗粒中丹参提取工艺的研究[J]. 药物评价研究, 2013, 0(4): 281-284 |
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| 作者姓名： | 闵建华 孟亚会 陈明民 章振鹏 孙亮 向飞军 |
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| 作者单位： | 广东康美药物研究院有限公司,广东广州510006 |
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| 摘 要： | 目的优选益气养心颗粒中丹参提取工艺。方法以丹参酮ⅡA、丹酚酸B的提取量和提取液浸膏得率为考察指标,采用正交设计,考察溶剂用量、提取次数、提取时间等对提取效果的影响。结果最佳提取工艺为用10倍量的50%乙醇提取3次,每次1h。结论优选的纯化工艺简单易行,适用于实际生产。
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| 关 键 词： | 益气养心颗粒 丹参 丹参酮ⅡA 丹酚酸B 正交试验 |
Extraction process of Salviae Miltiorrhizae Radix et Rhizoma in Yiqi Yangxin Granule |
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| MIN Jian-hua,MENG Ya-hui,CHEN Ming-min,ZHANG Zhen-peng,SUN Liang,XIANG Fei-jun. Extraction process of Salviae Miltiorrhizae Radix et Rhizoma in Yiqi Yangxin Granule[J]. Drug Evaluation Research, 2013, 0(4): 281-284 |
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| Authors: | MIN Jian-hua MENG Ya-hui CHEN Ming-min ZHANG Zhen-peng SUN Liang XIANG Fei-jun |
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| Affiliation: | Guangdong Kangmei Pharmaceutical Research Institute Co., Ltd., Guangzhou 510006, China |
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| Abstract: | Objective To optimize the extraction technology of Salvia Miltiorrhizae Radix et Rhizoma in Yiqi Yangxin Granule. Methods Using orthogonal test design, the effects of solvent amount, extracting times and extracting time on extraction were investigated using the amounts and extract yields of tanshinone IIA and salvianocilic acid B as indexes. Results The optimum extraction parameters were as follow： 10 times of 50% ethanol, extracting for 3 times and 1 h each time. Conclusion The purification process is simple and suitable for practical production. |
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| Keywords: | Yiqi Yangxin Granule Salvia Miltiorrhizae Radix et Rhizoma tanshinone IIA salvianocilic acid B orthogonal test |
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