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慢性乙型肝炎患者肝功能与血清HBVDNA负荷及肝脏病理的关系
引用本文:丁虹,陆忠华,蒋祥虎. 慢性乙型肝炎患者肝功能与血清HBVDNA负荷及肝脏病理的关系[J]. 临床肝胆病杂志, 2006, 22(3): 173-174
作者姓名:丁虹  陆忠华  蒋祥虎
作者单位:无锡市传染病医院,江苏,无锡,214005;无锡市传染病医院,江苏,无锡,214005;无锡市传染病医院,江苏,无锡,214005
摘    要:
探讨慢性乙型肝炎患者肝功能与血清HBVDNA负荷及肝脏病理的相关性。随机选择207例慢性乙型肝炎患者,检测其血清ALT、HBVDNA含量,肝穿刺活检,光镜多视野观察其肝组织的病理情况。随着慢性乙型肝炎患者血清ALT的升高,HBVDNA复制程度的增高,其肝组织的炎症活动度、纤维化程度明显升高(P<0.01)。慢性乙型肝炎患者血清ALT、HBVDNA含量与肝组织的炎症活动度、纤维化程度有相关性。

关 键 词:慢性乙型肝炎  肝组织  乙型肝炎病毒脱氧核糖核酸  肝功能
文章编号:1001-5256(2006)03-0173-02
收稿时间:2005-04-06
修稿时间:2005-07-13

The relationship between the liver function and contents of serum HBVDNA and hepatic pathology in patiens with chronic hepatitis B
DING Hong,LU Zhong-hua,JIANG Xiang-hu. The relationship between the liver function and contents of serum HBVDNA and hepatic pathology in patiens with chronic hepatitis B[J]. Chinese Journal of Clinical Hepatology, 2006, 22(3): 173-174
Authors:DING Hong  LU Zhong-hua  JIANG Xiang-hu
Affiliation:WuXi Hospital for Infections Disease, JiangSu, WuXi, 214005
Abstract:
To study on the relationship between the liver function and contents of serum HBVDNA and hepatic pathology in patiens with chronic hepatitis B.207 cases patiens with chronic hepatitis B collected by randam sampling method.Deteor their ALT and the HBVDNA in the serum and examined the liver tissue with pathological methods.Followed by the elevation of ALT and HBVDNA in the serum the liver tissnes inflammation actirity and fibrosis was obviously elevated.The result showed that the ALT in serum and the contents of HBVDNA in serum was correlated with the liver Inflammation activity and fibrosis of the patients with chronic hepatitis B(P<0.01).
Keywords:chronic hepatitis B  liver tissue  HBVDNA  liver function
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