三硝基甲苯作业工人晶体损害与其尿中2,6-二硝基-4-氨基甲苯含量的关系

目的 探讨三硝基甲苯（TNT）作业工人晶体损害与尿2，6－二硝基－4－氨基甲苯（DNAT）含量的关系。方法 作业工人散瞳后检查眼晶体，并且测定班后尿DNAT含量。结果 当作业工人晶体出现混浊时，尿中DNAT含量明显增加（2.38mg/L),其与接触TNT尚未出现晶体混浊组（1.44mg/L)比较，差异有显著性（P＜0．05）。结论 晶体混浊程度随尿DNAT含量的增高呈增加的趋势。ILO提出的DNAT30mg/L生物阈限值不适合我国职业人群。

Study on the relationship between the opacity of lens and the levels of 2,6-dinitro-4-amino-toluene(DNAT) in the urine of workers exposed to trinitrotoluene(TNT)

Objective To find out the relationship between the opacity in lens and the contents of 2,6-dinitro-4-amino-toluene(DNAT) in the urine of exposed workers. Methods Testing the exposed worker's lens and measuring the contents of DNAT in the urine after work. Results When the opacity of the lens occurred,the contents of DNAT in the urine(2.38 mg/L) of workers exposed to TNT were significantly higher than those without opacity in lens(1.44 mg/L)(P<0.05). Conclusion The severity of opacity of lens increased with the contents of DNAT raised in the urine.The threshold value suggested by ILO is not applicable to Chinese occupational population,which recommends the contents of DNAT(30 mg/L) in the urine for the workers exposed to TNT as biological occupational exposed limits.