| 莫西沙星序贯治疗社区获得性肺炎的临床分析 |
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| 引用本文： | 陈磊,虞亦鸣,赵汝霞,马红映,汪丽,吕婉飞,邓在春. 莫西沙星序贯治疗社区获得性肺炎的临床分析[J]. 中国现代医生, 2012, 0(36): 152-153 |
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| 作者姓名： | 陈磊 虞亦鸣 赵汝霞 马红映 汪丽 吕婉飞 邓在春 |
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| 作者单位： | [1]宁波市北仑区人民医院呼吸内科,浙江宁波315806 [2]宁波大学医学院附属医院呼吸内科,浙江宁波315020 |
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| 基金项目： | 浙江省医学会科研课题（2008ZYC40） |
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| 摘 要： | 目的研究莫西沙星序贯治疗礼区获得性肺炎的临床疗效与安全性。方法127例社区获得性肺炎患者随机分为莫西沙星研究组和头孢曲松／阿奇霉素对照组，治疗10d后，复查胸部CT、痰培养、痰支原体DNA检测进行疗效评估。结果治疗组与对照组临床有效率、细菌清除率分别为96．88％、84．13％和96．43％、85．19％，两组临床有效率比较，差异有统计学意义（P〈0．05），但细菌清除率差异无统计学意义（P〉0．05）。结论莫西沙星序贯治疗社区获得性肺炎效果可靠，可作为社区获得性肺炎抗菌治疗优选方案。
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| 关 键 词： | 社区获得性肺炎 莫西沙星 |
Clinical analysis of Moxifloxacin sequential therapy for CAP |
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| CHEN Lei,YU Yimin,ZHAO Ruxia,MA Hongying,WANG Li,LV Wanfei,DENG Zaichun. Clinical analysis of Moxifloxacin sequential therapy for CAP[J]. , 2012, 0(36): 152-153 |
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| Authors: | CHEN Lei YU Yimin ZHAO Ruxia MA Hongying WANG Li LV Wanfei DENG Zaichun |
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| Affiliation: | 1.Respiratory Medicine,Beilun District People＇s Hospital, Ningbo 315806, China;2.Respiratory Medicine,The .Affiliated Hospital of Ningbo University, Ningbo 315020, China) |
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| Abstract: | Objective To evaluate the clinical efficacy of Moxifloxacin sequential therapy for community acquired pneumo- nia （CAP）. Methods 127 cases of CAP were randomized into Moxifloxacin group and Cefiriaxone/Azithromycin group, sputum culture and detection of specific DNA of mycoplasma pneumoniae （MP） were underwent twice before and after treatment. Results The total efficacy rates and bacterial clean rates in Moxifloxacin group and Ceftriaxone/Azithromyein group were 96.88% ,84.13% and 96.43% ,85.19% respectively, and the difference of the total efficacy rates between the two groups were statistically significant, but the difference of the bacterial clean rates between the two groups were not statistically significant. Conclusion It suggested that Moxifloxacin is a more effective drug for CAP. |
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| Keywords: | CAP Moxifloxacin |
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