欧洲心脏手术风险评估系统对冠状动脉旁路移植术后患者生存质量的预测价值

目的 初步评估欧洲心脏手术风险评估系统(EuroSCORE)对冠状动脉旁路移植术后患者生存质量的预测价值.方法 对2002年12月至2007年12月期间接受冠状动脉旁路移植术的患者进行术前EuroSCORE风险评估.通过发放诺丁汉健康调查问卷、西雅图心绞痛问卷和杜克活动问卷对术后患者进行生存质量调查,并以上述3份量表为结局变量,分析患者术前EuroSCORE评分是否对患者术后远期生存质量具有预测功能.结果 患者术前EuroSCORE评分与术后生存质量评分存在一定程度的相关性(r值:0.010～0.276),尤其在涉及机体功能改善方面的亚组中相关性更强(r＞0.2).线性回归分析显示,EuroSCORE评分与生存质量评分之间存在线性关系(P＜0.05),但线性关系较弱(r~2＜0.1).结论 接受冠状动脉旁路移植术患者的术前EuroSCORE评分与术后生存质量评分相关性较弱,不能作为患者术后远期生存质量优劣的预测性指标.

The role of European system for cardiac operative risk evaluation in the prediction of quality of life in patients after coronary artery bypass graft surgery

Objective To assess the value of European system for cardiac operative risk evaluation (EuroSCORE) in predicting quality of life in patients post coronary artery bypass graft surgery (CABG).Methods A total of 387 patients underwent CABG in our institute from December of 2002 to December of 2007 were assessed by EuroSCORE before operation. Health-related quality of life(QoL) was estimated postoperatively with Seattle angina questionnaire (SAQ),Nottingham healthy profile (NHP) and Duke activity status index (DASI) in order to evaluate the value of EuroSCORE for predicting quality of life in patients post CABG.Results There were statistically significant but weak correlations between postoperative QoL score and preoperative EuroSCORE score(r:0.010-43.276).Emotional and psychological experience subgroup analysis showed better predictive value of EuroSCORE score on postoperative QoL score in improved physical functioning subgroups(r＞0.2).Linear regression analysis showed that EuroSCORE score was significant but weakly (r~2＜0.1) correlated with postoperative QoL score(P＜0.05).Conclusion Preoperative EuroSCORE score is weakly correlated with postoperative QoL score in patients post CABG.