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| 甲硝唑和替硝唑体外抑制阴道毛滴虫疗效比较 | |
| 引用本文： | 毛明辉,侯欣喜,刘俊,张欢欢,万殊岑,徐慧,毛川江,杨宗琪,赵勇. 甲硝唑和替硝唑体外抑制阴道毛滴虫疗效比较[J]. 亚太传统医药, 2011, 7(6): 102-103 |
| 作者姓名： | 毛明辉 侯欣喜 刘俊 张欢欢 万殊岑 徐慧 毛川江 杨宗琪 赵勇 |
| 作者单位： | 川北医学院病原中心,四川南充,637007 |
| 摘 要： | 目的:比较甲硝唑、替硝唑体外抑制阴道毛滴虫的疗效,为临床应用提供参考依据。方法:设置实验组与对照组,实验组加入含不同浓度的甲硝唑和替硝唑无菌生理盐水0.5mL。向两组加入混匀后等量(0.1mL)活虫率均为90%以上的滴虫悬液,24h后用显微镜观察,计算出两药的抑制率。结果:培养24h后,①随着两药浓度的升高,其抑制率也升高;②同浓度下替硝唑抑制率高于甲硝唑;③在低于200μg/mL时,甲硝唑和替硝唑抑制作用相差不大,而高于200μg/mL时,替硝唑的抑制作用明显高于甲硝唑;④药物浓度低于500μg/mL时,甲硝唑和替硝唑抑制率均不高于20%,而高于500μg/mL时,甲硝唑和替硝唑抑制作用明显增强。结论:甲硝唑和替硝唑在高浓度时均有良好的抑制作用,但同浓度下替硝唑的抑制效果要优于甲硝唑。 |
| 关 键 词： | 甲硝唑 替硝唑 阴道毛滴虫 体外抑制 |
Comparative Effects of Metronidazole and Tionidazole on Trichomonas Vaginalis in Vitro |
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| Mao Minghui,Hou Xinxi,Liu Jun,Zhang Huanhuan,Wan Shucen,Xu Hui,Mao Chuanjiang,Yang Zhongqi,Zhao Yong. Comparative Effects of Metronidazole and Tionidazole on Trichomonas Vaginalis in Vitro[J]. Asia-Pacific Traditional Medicine, 2011, 7(6): 102-103 | |
| Authors: | Mao Minghui Hou Xinxi Liu Jun Zhang Huanhuan Wan Shucen Xu Hui Mao Chuanjiang Yang Zhongqi Zhao Yong |
| Affiliation: | Mao Minghui,Hou Xinxi,Liu Jun,Zhang Huanhuan,Wan Shucen,Xu Hui,Mao Chuanjiang,Yang Zhongqi,Zhao Yong(The Microorganism Research Center,North Sichuan Medical College,Nanchong 637000,China) |
| Abstract: | Objective:To compare the effects of metronidazole and tionidazole on trichomonas vaginalis in vitro,providing for clinical application.Methods:The research had the experiment group and control group,which were added with the same amount(0.1mL)of trichomonas vaginalis,above 90% was alive.The experiment group was added with 0.5mL of the normal saline,in which the metronidazole or tionidazole was of different concentrations.After cultivating for 24 hours,the experiment was observed under the microscope and the... |
| Keywords: | Metronidazole Tionidazole Trichomonas Vaginalis Inhibitions in Vitro |
| 本文献已被 CNKI 维普 万方数据 等数据库收录！ | |