体外受精胚胎移植治疗原发性不孕症疗效分析

目的分析输卵管因素与不明原因原发不孕患者行常规体外受精-胚胎移植术（IVF—ET，in vitro fertilization and embryo transfer）时的受精率、完全受精失败率及临床妊娠率，评估常规体外授精方式的效果。方法将213例原发不孕患者分为输卵管因素组188例，不明原因组25例，行IVF—ET，比较二组的受精率、完全受精失败率及临床妊娠率。结果不明原因纽受精率明显低于输卵管因素组（P〈0．01），而完全受精失败率明显高于后者（P〈0．05），二者临床妊娠率差异无统计学意义。结论原发不孕输卵管因素患者最好选择IVF；不明原因不孕患者可以采用部分IVF部分ICSI的治疗方案。

Analysis of effect of in vitro fertilization and embryo transplantation in treatment of tubal infertility and unexplained infertility

Objective To analyze the fertilization rate and complete fertilization failure rate and pregnancy rate of tubal infertility and unexplained infertility patients treated with in vitro fertilization and embryo transplantation （ IVF - ET） and evaluate the results of in vitro insemination. Methods The 213 primary infertility patients were divided into tubal infertility group consisted of 188 cases and unexplained infertility group consisted of 25 cases. The fertilization rate, complete fertilization failure rate and clinical pregnancy rate between the two groups were compared. Results The fertilization rate in unexplained infertility group was significantly lower than that of tubal infertility group （P 〈 0.01 ）, while the complete fertilization failure rate in unexplained infertility group was higher than that of tubal infertility group （ P 〈 0.05 ）. There was no significantly statistical difference in clinical pregnancy rate between the two groups. Conclusion The tubal primary infertility patients be treated with IVF and the unexplained primary infertility patients be treated with IVF- ICSI split insemination method.