| 射干合剂治疗小儿咳嗽的随机、阳性药对照、大样本临床试验 |
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| 引用本文： | 朱鹏程,吴敏,时毓民,张欣,秦丽萍,赵欣.射干合剂治疗小儿咳嗽的随机、阳性药对照、大样本临床试验[J].上海中医药杂志,2016,50(9):48-51. |
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| 作者姓名： | 朱鹏程 吴敏 时毓民 张欣 秦丽萍 赵欣 |
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| 作者单位： | 上海交通大学医学院附属新华医院中医科,上海,200092,上海交通大学医学院附属新华医院中医科,上海,200092,复旦大学附属儿科医院中医科,上海,200032,上海交通大学医学院附属新华医院中医科,上海,200092,上海交通大学医学院附属新华医院中医科,上海,200092,上海交通大学医学院附属新华医院中医科,上海,200092 |
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| 基金项目： | 上海市科委中医重点项目(13401902700) |
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| 摘 要： | 目的观察射干合剂治疗小儿咳嗽的临床疗效。方法将285例咳嗽患儿随机分为治疗A组、治疗B组及对照组,每组90例。在常规治疗的基础上,治疗A组加用射干合剂、治疗B组加用宣肺止嗽合剂、对照组加用氨溴特罗口服液治疗。各组疗程均为7天,观察临床疗效及中医证候的变化情况。结果 1试验期间,各组共脱落15例,脱落率5.26%(10%);最终完成试验者270例,每组90例。2治疗A组、治疗B组及对照组临床总有效率分别为91.11%、80.00%和77.78%;组间临床疗效比较,差异有统计学意义,治疗A组明显优于治疗B组、对照组(P0.05)。3治疗前后组内比较,各组中医证候积分差异均有统计学意义(P0.05)。组间治疗后总体比较,中医证候积分差异有统计学意义(P0.05);其中治疗A组中医证候积分减分差值显著大于治疗B组、对照组(P0.05);治疗B组与对照组中医证候积分减分差值差异无统计学意义(P0.05)。结论射干合剂治疗小儿咳嗽的疗效满意,可显著缓解患儿的临床症状。
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| 关 键 词： | 小儿咳嗽 射干合剂 阳性药物对照 射干麻黄汤 |
| 收稿时间： | 2016/3/16 0:00:00 |
Clinical research on infantile cough treated with Shegan Mixture:a randomized trials with positive controlled drug and large samples |
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| ZHU Peng-cheng,WU Min,SHI Yu-min,ZHANG Xin,QIN Li-ping and ZHAO Xin.Clinical research on infantile cough treated with Shegan Mixture:a randomized trials with positive controlled drug and large samples[J].Shanghai Journal of Traditional Chinese Medicine,2016,50(9):48-51. |
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| Authors: | ZHU Peng-cheng WU Min SHI Yu-min ZHANG Xin QIN Li-ping and ZHAO Xin |
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| Institution: | Department of Traditional Chinese Medicine, Xinhua Hospital Affiliated to Medical School of Shanghai Jiaotong University,Shanghai,200092,Department of Traditional Chinese Medicine, Xinhua Hospital Affiliated to Medical School of Shanghai Jiaotong University,Shanghai,200092,Department of Traditional Chinese Medicine, Paediatrics Hospital Affiliated to Fudan University,Shanghai,200032,Department of Traditional Chinese Medicine, Xinhua Hospital Affiliated to Medical School of Shanghai Jiaotong University,Shanghai,200092,Department of Traditional Chinese Medicine, Xinhua Hospital Affiliated to Medical School of Shanghai Jiaotong University,Shanghai,200092 and Department of Traditional Chinese Medicine, Xinhua Hospital Affiliated to Medical School of Shanghai Jiaotong University,Shanghai,200092 |
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| Abstract: | |
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| Keywords: | infantile cough Shegan mixture positive control drug Shegan Mahuang Decoction |
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