基于中医传承辅助平台的针灸治疗失眠选穴组方规律分析

目的运用中医传承辅助平台(V2.5),基于临床文献挖掘、分析针灸治疗失眠的穴位配伍规律,总结针灸治疗失眠的核心处方。方法检索1997~2015年中国知网期刊数据库收录的针灸治疗失眠的临床研究文献,将其中的辨证分型、穴位处方等信息录入中医传承辅助平台,采用软件集成的数据挖掘方法,分析其中的穴位配伍规律。结果 1共纳入86篇文献、237首穴位处方,涉及10个证型,其中以心脾两虚证(21.9%)和肝郁化火证(21.5%)最为多见;2使用频次较高的穴位依次为神门(80.6%)、百会(68.8%)、三阴交(61.2%)、四神聪(56.5%)、内关(54.0%)等;3设定置信度为0.8、支持度为47,得到23组穴位;4设置相关度为8、惩罚度为2,得到核心处方7首。结论中医传承辅助平台是一种挖掘和分析针灸选穴配伍规律的重要辅助工具,本研究得到的穴位配伍规律和核心处方可为临床治疗失眠提供参考。

Acupuncture points prescription for insomnia on TCMISS

  Objective:With the help of software TCMISS(V2.5), the key acupuncture points for insomnia are determined by data retrieval on the basis of clinical literature. MethodsThe acupuncture points formula for insomnia between 1997 and 2015 were screened from CNKI database and then input into software TCMISS for data mining and analysis.  Results:Totally there are 237 formulas in 86 articles selected for insomnia, involving 10 syndromes; the most common syndromes are heart-spleen deficiency(21.9%) and liver depression-forming fire(21.5%). The most frequently-used points are Shenmen(HT 7), Baihui(GV 20), Sanyinjiao(SP 6), Sishenchong(EX-HN 1) and Neiguan(PC 6). When the confidence score is set as 0.8 and support score as 47,3 formulas were screened; when the the relevancy is set as 8 and punishment degrees as 2,7 core point formulas are screened.  Conclusion:The platform of TCMISS is a very useful tool for screening acupuncture formulas, and he key point formulas help clinical treatment for insomnia.