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相对响应系数法辅助测定中药多成分含量的研究
引用本文:李铮,王旭,邬国庆,张小茜,方颖. 相对响应系数法辅助测定中药多成分含量的研究[J]. 中国中药杂志, 2008, 33(17): 2097-2099
作者姓名:李铮  王旭  邬国庆  张小茜  方颖
作者单位:1. 北京市药品检验所,北京,100035
2. 国家药典委员会,北京,100061
基金项目:国家中医药管理局中医药科学技术研究专项基金 
摘    要:
目的:建立采用系数计算通过一个对照品,计算出多个成分的含量的方法,以全面控制药品质量。方法:基于Lambert-Beer定律,用高效液相色谱法测定峰面积,折算出2个成分的计算系数。结果:测得了4组成分的系数,并进行了验证,结果较满意。结论:该方法在一定范围内可行。

关 键 词:系数计算  HPLC  折算
收稿时间:2008-03-06

Investigation of multi-composition in traditional Chinese medicine by module calculation
LI Zheng; WANG Xu; WU Guo-qing; ZHANG Xiao-qian; Fang Ying. Investigation of multi-composition in traditional Chinese medicine by module calculation[J]. China Journal of Chinese Materia Medica, 2008, 33(17): 2097-2099
Authors:LI Zheng   WANG Xu   WU Guo-qing   ZHANG Xiao-qian   Fang Ying
Abstract:
Objective: To establish a method for the determination of multi-composition in traditional Chinese medicine by module calculation. Method: In view of the law of lambert-beer, the modulue of two compositions was converted on basis of peak area by HPLC. Result: The modulues of four groups were gotten and the effects of validation were well. Conclusion: The method was feasible and could be used within a certain range.
Keywords:module calculation   convert   HPLC
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