儿童神经母细胞瘤的CT诊断

目的探讨儿童神经母细胞瘤的CT表现，以提高对本病的认识。方法回顾性分析11例经病理证实的儿童神经母细胞瘤的CT表现，包括肿瘤部位、大小、边缘、密度、强化程度、转移等。其中5例仅行CT平扫，6例行CT平扫及增强。结果11例中，源于肾上腺8例，源于腹部交感神经链2例，源于后纵隔交感神经链1例；10例肿块呈不规则分叶状，直径2．5-11cm。边界不清，10例肿块密度不均匀、可见囊变或钙化。在6例增强扫描中，6例都呈不均匀强化。转移常见，其中淋巴结转移3例，骨转移1例，肺转移1例。结论儿童神经母细胞瘤CT表现有一定的影像特征，有助于提高临床诊断。

The CT diagnosis of neuroblastoma in children

Objective To summarize the CT scan finding of neuroblastoma in children, for the purpose of increasing the diagnostic ability to this disease. Methods CT findings in 11 children with neurobiastoma proven by surgery and pathology were collected. In these cases, 5 underwent plain CT scan, 6 underwent both plain and contrast-unenhanced CT scan. Features of the lesions, including site, size, margin, density, enhancement, metastasis were analyzed retrospectively. Results In 11 cases, maximum diameter of tumors ranged from 2.5cm to 1 lcm, 8 cases were found in adrenal gland, 2 cases were found in abdominal sympathetic chain, 1 case was found in sympathetic chain of posterior mediastinum. Irregular lobulated shape was demonstrated in 10 cases. Ill-definite margin demonstrated in cases. Metastasis was frequently observed, the cases of osseous, pulmonary and lymphatic metastasis were 1, 1, and 3 respectively. In 6 contrast-unenhanced CT scan cases, all demonstrated heterogeneous en- hancement. Conclusion Certain characteristic was observed in CT finding of neuroblastoma, which can contribute to diagnosis and differential diagnosis.