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大剂量促红细胞生成素治疗肾性贫血的疗效观察
引用本文:张萍,梁劲松.大剂量促红细胞生成素治疗肾性贫血的疗效观察[J].中国药房,2005,16(13):1009-1010.
作者姓名:张萍  梁劲松
作者单位:贵州省黔南州人民医院肾内科,都匀市,558000
摘    要:目的:观察大剂量促红细胞生成素治疗肾性贫血的疗效和安全性。方法:将60例肾性贫血患者随机分为治疗组和对照组。治疗组给予促红细胞生成素9000IU皮下注射,1次/wk;对照组给予促红细胞生成素3000IU皮下注射,3次/wk,均连用6wk。结果:治疗组和对照组的有效率分别为93.3%、90.0%(P>0.05),但前者较后者每周注射次数减少,费用低,且不良反应无明显增加。结论:大剂量促红细胞生成素治疗肾性贫血疗效确切、安全、可靠。

关 键 词:慢性肾功能衰竭  贫血  促红细胞生成素  疗效
文章编号:1001-0408(2005)13-1009-02
修稿时间:2005年4月5日

Observation of Therapeutic Effects of Large Dose of Erythropoietin in the Treatment of Patients with Renal Anemia
ZHANG Ping,LIANG Jingsong.Observation of Therapeutic Effects of Large Dose of Erythropoietin in the Treatment of Patients with Renal Anemia[J].China Pharmacy,2005,16(13):1009-1010.
Authors:ZHANG Ping  LIANG Jingsong
Abstract:OBJECTIVE:To observe the curative effects and safety of large dose of erythropoietin in the treatment of renal anemia.METHODS:60patients with renal anemia were randomized into treatment group and control group.The treatment group was given erythropoietin9000IU by hypodermic injection once a week;the control group was treated with erythropoietin3000IU by hypodermic injection3times a week.The course of treatment for both group were6successive weeks.RESULTS:The effective rates of the treatment group and the control group were93.3%and90.0%(P>0.05)respectively,but the weekly injection times of the treatment group were reduced and the cost was lower as against the control group and there was no significant increase of adverse reactions in the treatment group.CONCLUSION:It is effective,safe and reliable to use large dose of erythropoietin in the treatment of renal anemia.
Keywords:Chronic renal failure  Anemia  Erythropoietin  Curative effects
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