Severe osteoarticular infection associated with Panton-Valentine leukocidin-producing Staphylococcus aureus |
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| Authors: | Moumile Kaoutar Cadilhac Céline Lina Gérard Berche Patrick Glorion Christophe Ferroni Agnès |
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| Affiliation: | 1. Laboratoire de Microbiologie, AP-HP, Hôpital Necker-Enfants Malades, 75015 Paris, France;2. Service de Chirurgie Orthopédique Pédiatrique, AP-HP, Hôpital Necker-Enfants Malades, 75015 Paris, France;3. Centre National de Référence des Staphylocoques, Hôpital Edouard Herriot, 69003 Lyon, France;1. Great Ormond Street Hospital for Children NHS Foundation Trust, London, UK;2. Imperial College Healthcare NHS Trust, Queen Charlotte''s and Chelsea Hospital and St Mary''s Hospital, London, UK;3. Healthcare Associated Infections and Antimicrobial Resistance Division, National Infection Service, Public Health England, London, UK;4. North West London Health Protection Team, Public Health England, London, UK;5. National Infection Service, Public Health England, London, UK;1. Department of Medical Microbiology and Parasitology, School of Medical Sciences, Universiti Sains Malaysia, 16150 Kubang Kerian, Kelantan, Malaysia;2. Hospital Universiti Sains Malaysia, Health Campus, USM, 16150 Kubang Kerian, Kelantan, Malaysia;3. Acarology Unit, Infectious Disease Research Centre, Institute for Medical Research, Ministry of Health Malaysia, National Institutes of Health Complex, Bandar Setia Alam, 40170 Shah Alam, Selangor, Malaysia |
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| Abstract: | ![]()
We report here a case of osteoarticular infection associated with Panton-Valentine leukocidin-producing Staphylococcus aureus. The 3-year-old child presented osteoarthritis associated with toxic shock syndrome, which was complicated by thrombosis, pneumonia, and diaphysitis, despite appropriate antibiotic treatment. Osteitis associated with toxinogenic S. aureus is rarely described. This case highlights the need of early and aggressive surgical treatment, in addition to appropriate antimicrobial therapy. |
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