射频技术在肝细胞癌临床应用中的选择、疗效与思考

射频消融为治疗肝细胞癌的重要方法,具有微创性,可重复性,疗效确切等优点.对于不适宜手术及肝移植的早期肝细胞癌患者,许多中心已将其作为一种有效的手段.笔者回顾了射频治疗肝细胞癌的适应证、技术及疗效.我们体会,对于射频治疗,合理选择患者、优化治疗方案、完全灭活肿瘤与术后密切随访非常重要.新技术的应用,如人工胸水与腹水辅助穿刺、实时超声造影术中引导,腹腔镜与开腹射频,更有助于拓展射频治疗的适应证,减少术后并发症.

Abstract：

Radiofrequency ablation (RFA) has been playing an important role in the treatment of hepatocellular carcinoma (HCC). It is minimally invasive, easily repeatable and potentially curative. Many centers now accept it to be the best therapeutic choice for patients with early-stage HCC when liver transplantation or surgical resection is not suitable. In this article, we reviewed the indications, techniques , and clinical results of RFA in the treatment of HCC.Suitable patient selection, good pre-treatment planning,complete ablation, and careful post-treatment follow up are important. Techniques, such as artificial pleural effusion and ascites, contrast-enhanced ultrasonography-guided RFA,laparoscopic or open surgical approaches have reduced complications and expanded the indications for RFA.

Radiofrequency ablation for hepatocellular carcinoma: our perspectives on patient selection and curative results

Radiofrequency ablation (RFA) has been playing an important role in the treatment of hepatocellular carcinoma (HCC). It is minimally invasive, easily repeatable and potentially curative. Many centers now accept it to be the best therapeutic choice for patients with early-stage HCC when liver transplantation or surgical resection is not suitable. In this article, we reviewed the indications, techniques , and clinical results of RFA in the treatment of HCC.Suitable patient selection, good pre-treatment planning,complete ablation, and careful post-treatment follow up are important. Techniques, such as artificial pleural effusion and ascites, contrast-enhanced ultrasonography-guided RFA,laparoscopic or open surgical approaches have reduced complications and expanded the indications for RFA.