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风湿性心脏病心房颤动患者发生动脉血栓栓塞危险因素的病例对照研究
引用本文:王春宁,高润霖,向菊兰,曹红,程岩,许美龄.风湿性心脏病心房颤动患者发生动脉血栓栓塞危险因素的病例对照研究[J].中国循环杂志,2003,18(2):115-117.
作者姓名:王春宁  高润霖  向菊兰  曹红  程岩  许美龄
作者单位:1. 100037,北京市,中国医学科学院,中国协和医科大学,心血管病研究所,阜外心血管病医院,心内科
2. 100037,北京市,中国医学科学院,中国协和医科大学,心血管病研究所,阜外心血管病医院,病案室
摘    要:目的 :试图找出风湿性心脏病心房颤动 (房颤 )患者发生动脉血栓栓塞的危险因素 ,为提出预防措施提供依据。方法 :对 1977年 1月至 1996年 12月在我院住院的风湿性心脏病房颤患者其病史中发生过动脉血栓栓塞的 92例患者进行了 1∶1配对病例对照研究。结果 :单因素分析中 ,风湿性心脏病房颤患者发生动脉血栓栓塞的危险因素是合并高血压史、瓣膜疾病史 >10年。多因素Logistic回归分析及条件Logistic回归分析显示重要的有统计学意义的危险因素是风湿性瓣膜疾病史 >10年。结论 :重要的有统计学意义的危险因素是风湿性瓣膜疾病史 >10年。

关 键 词:风湿性心脏病  心房颤动  血栓栓塞  危险因素
文章编号:1000-3614(2003)02-0115-03
修稿时间:2002年5月16日

A Case-Controled Study for Detecting Risk Factors of Thromboembolism in Patients With Rheumatic Heart Disease and Atrial Fibrillation
Wang Chunning,Gao Runlin,Xiang Julan,et al..A Case-Controled Study for Detecting Risk Factors of Thromboembolism in Patients With Rheumatic Heart Disease and Atrial Fibrillation[J].Chinese Circulation Journal,2003,18(2):115-117.
Authors:Wang Chunning  Gao Runlin  Xiang Julan  
Abstract:Objective: To determine the risk factors of arterial thromboembolism in patients with rheumatic heart disease and atrial fibrillation in order to identify high risk population. Methods: A matched case-control study was performed in 92 patients with arterial thromboembolism,who had suffered from rheumatic heart disease and atrial fibrillation,and admitted to our hospital from January,1977 to December,1996. Results: In univariate analysis,the statistically significant risk factors of arterial thromboembolism were the complicated hypertension and valvular disease history(>10 years). Logistic regression analysis revealed that valvular disease history(>10 years) was the risk factor of arterial thromboembolism. Conclusion: The important risk factor of arterial thromboembolism in patients with rheumatic heart disease and atrial fibrillation is valvular disease history >10 years.
Keywords:Rheumatic heart disease  Atrial fibrillation  Arterial thromboembolism  Risk factor  
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