| 瑞格列奈与格列吡嗪治疗2型糖尿病的疗效比较 |
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| 引用本文： | 汤广锋,徐雯,杨玉红,李昉,唐同翠.瑞格列奈与格列吡嗪治疗2型糖尿病的疗效比较[J].安徽卫生职业技术学院学报,2008,7(1):32-33. |
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| 作者姓名： | 汤广锋 徐雯 杨玉红 李昉 唐同翠 |
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| 作者单位： | 滁州市第一人民医院,安徽,239000 |
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| 摘 要： | 目的：比较瑞格列奈和格列吡嗪治疗2型糖尿病的疗效差异。方法：将单纯饮食控制或加用盐酸二甲双胍药物治疗不满意的2型糖尿病86例患者随机分成瑞格列奈组46例和格列吡嗪组42例，疗程12周。监测两组治疗前及治疗后的空腹及餐后2h血糖，治疗前及治疗后12周糖化血红蛋白（HbA1C）、总胆固醇、甘油三脂和体重的变化，并观察有否低血糖等不良反应。结果：瑞格列奈和格列吡嗪对空腹血糖均有显著性下降，两药降低幅度无统计学意义（P〉0．05），而对餐后2h血糖的疗效高于格列吡嗪（P〈0．01），两药能明显降低HbA1C，但瑞格列奈疗效优于格列吡嗪（P〈0．05）。结论：瑞格列奈和格列吡嗪对空腹血糖均有显著性下降，但瑞格列奈控制餐后高血糖和HbA1C明显优于格列吡嗪。
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| 关 键 词： | 瑞格列奈 格列吡嗪 2型糖尿病 血糖 |
Comparison between curative Effects of Repaglinide and of Glipizide on the Type 2 Diabetes |
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| TANG Guang-feng,XU Wen,YANG Yu-hong,LI Fang,TANG Tong-cui.Comparison between curative Effects of Repaglinide and of Glipizide on the Type 2 Diabetes[J].Journal of Anhui Heaith Vocational & Technical College,2008,7(1):32-33. |
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| Authors: | TANG Guang-feng XU Wen YANG Yu-hong LI Fang TANG Tong-cui |
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| Institution: | Department of Endocrinology,the First People\'s Hospital of Chuzhou,Anhui 239000,China TANG Guang-feng,XU Wen,YANG Yu-hong,LI Fang,TANG Tong-cui |
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| Abstract: | Objective To compare the clinical effect of Repaglinide and Glipizide on the type 2 diabetes Methods 86patients with type 2 diabetes including no satisfactory efficacy with controlled diet alone or/and combined diabex management were randomly divided into two groups:repaglinide group(n=44 cases) and glipiaide group(n=42 cases). The clinical course investigated was twelve weeks, treated with Repaglinide and Glipiaide for 12 weeks, and kept close watch on FBG(fasting blood glucose), 2hPG, HbA1c, TC, Weight, T... |
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| Keywords: | Repaglinide Glipiaide Type 2 diabetes Blood glucose FBG 2hPG HbA1c |
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