| 替吉奥联合顺铂新辅助化疗在胃癌中的应用 |
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| 引用本文： | 王舟翀. 替吉奥联合顺铂新辅助化疗在胃癌中的应用[J]. 国际肿瘤学杂志, 2008, 35(7): 522-524 |
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| 作者姓名： | 王舟翀 |
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| 作者单位： | 上海市交通大学医学院附属新华医院普外科,200092 |
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| 摘 要： | 替吉奥(S-1)是一种第4代氟尿嘧啶衍生物口服抗癌剂,包括替加氟(FT)和两类调节剂吉美嘧啶及奥替拉西.日本目前晚期胃癌化疗80%以上病例使用S-1,有效率可达44.6%.新辅助化疗能减少肿瘤负荷,降低原发肿瘤分期,增加手术切除的可能性.替吉奥联合顺铂作为一种新的新辅助化疗方案,治疗胃癌总缓解率达76%,足目前为止进展期胃癌化疗方案中缓解率最高的方案.
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| 关 键 词： | 化学疗法 辅助 胃肿瘤 顺铂 替吉奥 |
S-1 combined with cisplatin neoadjuvant chemotherapy in gastric carcinoma |
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| WANG Zhou-chong. S-1 combined with cisplatin neoadjuvant chemotherapy in gastric carcinoma[J]. Journal of International Oncology, 2008, 35(7): 522-524 |
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| Authors: | WANG Zhou-chong |
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| Abstract: | S-1 is a kind of fouth-generation oral fluoropyrimidine,including tegafur(FT),5-chloro-2,4-dihydroxypyridine(CDHP),and potassium oxonate(Oxo).S-1 is now used in 80% advanced gastric cancer patients in Japan,it's reported that CR+RR is over 44.6%.Neoadjuvant chemotherapy can reduce tumor loading,degrade the staging,afford operation possibility.S-1 combined with CDDP as a new neoadjuvant chemotherapy,is the most efficient therapy in advanced gastric cancer at present,it's CR can be over 76%. |
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| Keywords: | Chemotherapy,adjuvant Stomach neoplasms Cisplatin S-1 |
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