| 人造板材释放的甲醛对小鼠骨髓细胞微核率影响 |
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| 引用本文： | 赵倩 段丽菊 刘英帅 鲁志松 乔琰 严彦 杨旭. 人造板材释放的甲醛对小鼠骨髓细胞微核率影响[J]. 公共卫生与预防医学, 2004, 15(6): 18-20 |
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| 作者姓名： | 赵倩 段丽菊 刘英帅 鲁志松 乔琰 严彦 杨旭 |
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| 作者单位： | [1]华中师范大学生命科学学院 [2]河南煤炭卫生学校基础医学教研室，平顶山467013 |
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| 基金项目： | 国家“十五”科技攻关项目 (2 0 0 1BA70 4B0 1) |
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| 摘 要： | 目的 探讨不同浓度气态甲醛对暴露小鼠的骨髓嗜多染红细胞微核的诱发效应。方法用不同剂量气态甲醛对小鼠进行连续动态染毒处理72h，取小鼠骨髓细胞制片，观察小鼠骨髓嗜多染红细胞微核形成率，从而判断气态甲醛对小鼠骨髓嗜多染红细胞微核的诱发效应。结果经甲醛染毒处理后，小鼠骨髓嗜多染红细胞微核率逐渐升高，与对照组相比有极显著性意义。结论甲醛可不同程度地影响小鼠骨髓嗜多染红细胞的微核形成率，并呈良好的剂量一效应关系。
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| 关 键 词： | 甲醛 小鼠 骨髓细胞 人造板材 微核率 动物实验 |
| 文章编号： | 1006-2483(2004)06-0018-03 |
| 修稿时间： | 2004-09-12 |
Effect of Formaldehyde from Artificial Based Boards on Micronucleus of Mice Marrow Polychromatic Erythrocyte |
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| ZHAO Qian,DUAN Li-ju LIU Ying-shuai,LU Zhi-song,QIAO Yan,YAN Yan,YANG Xu. Staff Room of Basic Midicine,Coal Sanitation School of Henan,PingDingsan ,China. Effect of Formaldehyde from Artificial Based Boards on Micronucleus of Mice Marrow Polychromatic Erythrocyte[J]. Journal of Public Health and Preventive Medicine, 2004, 15(6): 18-20 |
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| Authors: | ZHAO Qian DUAN Li-ju LIU Ying-shuai LU Zhi-song QIAO Yan YAN Yan YANG Xu. Staff Room of Basic Midicine Coal Sanitation School of Henan PingDingsan China |
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| Affiliation: | ZHAO Qian,DUAN Li-ju LIU Ying-shuai,LU Zhi-song,QIAO Yan,YAN Yan,YANG Xu. Staff Room of Basic Midicine,Coal Sanitation School of Henan,PingDingsan 467013,China |
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| Abstract: | Objective To investigate the effects induced by various concentrations of gaseous formaldehyde on the formation of micronucleus in mice marrow polychr omatic erythrocyte.MethodsMice were consistently exposed to different doses of gaseous formaldehyde for 72 hours; MN formation rate in marrow PCE was detected.ResultsCompared with the control, MN formation rate increases significantly.Conclusion Different concentrations of formaldehyde can affect the formation of MN in marrow PCE respectively, which showed a significant dose-related effect. |
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| Keywords: | formaldehyde mice marrow polychromatic erythrocyte micronuleus |
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