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外源基因在转基因蚊虫中表达的研究进展
引用本文:丁雪冰,陈晓光. 外源基因在转基因蚊虫中表达的研究进展[J]. 寄生虫与医学昆虫学报, 2008, 15(2): 108-114
作者姓名:丁雪冰  陈晓光
作者单位:南方医科大学公共卫生与热带医学学院病原生物学系,广州,510515;南方医科大学公共卫生与热带医学学院病原生物学系,广州,510515
摘    要:
利用转基因技术对蚊虫进行遗传修饰使其密度下降或降低其传播疾病的能力是控制蚊媒传染病的一个新策略。其核心问题是外源基因在转基因蚊虫体内的表达。本文从转基因蚊虫的表达载体、外源基因表达特性及效应、转基因蚊虫研究存在的问题及发展前景等方面对该领域的研究进展进行了综述。

关 键 词:外源基因  转基因蚊虫  转基因体系  表达特性  表达效应

HETEROLOGOUS EXPRESSION IN TRANSGENIC MOSQUITOES
DING Xue-Bing,CHEN Xiao-Guang. HETEROLOGOUS EXPRESSION IN TRANSGENIC MOSQUITOES[J]. Acta Parasitologica et Medica Entomologica Sinica, 2008, 15(2): 108-114
Authors:DING Xue-Bing  CHEN Xiao-Guang
Affiliation:DING Xue-Bing CHEN Xiao-Guang ( Department of Parasitology, School of Public Health and Tropical Medicine, Southern Medical University, Guangzhou 510515, China )
Abstract:
Mosquitoes are vectors of serious human infectious diseases,such as malaria,dengue and yellow fever.Genetically modification of mosquitoes has been proposed as a new strategy to control mosquito-borne diseases.The central event in transgenic mosquitoes is the heterologous expression of exo-genes.This review addresses mainly the relevant progress in the field of heterologous expression in transgenic mosquitoes such as transgenic mosquitoes expression vectors,heterologus expression characteristics and effect in transgenic mosquitoes and some points need to be attended in the future study.
Keywords:Heterologous expression  Transgenic mosquitoes  Transgenic systems  Expression characteristics  Effect of the expression
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