| 中风后抗抑郁治疗对神经功能康复疗效的临床意义 |
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| 引用本文： | 吴彩堂. 中风后抗抑郁治疗对神经功能康复疗效的临床意义[J]. 临床荟萃, 2009, 24(4): 310-313 |
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| 作者姓名： | 吴彩堂 |
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| 作者单位： | 厦门市第一医院杏林院区,神经内科,福建,厦门,361022 |
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| 摘 要： | 目的探讨治疗中风后抑郁对神经功能康复疗效的临床意义。方法选取脑卒中后并发抑郁症的患者81例,随机分为治疗组41例（男23例,女18例）,对照组40例（男21例,女19例）,对照组按病情分别给予抗凝、溶栓、脱水、利尿、降压、降血糖及营养脑神经等常规治疗;治疗组则在此基础上加服氟西汀（百忧解）胶囊（20mg／d）。疗程3个月。治疗前和治疗后1个月、3个月和6个月进行汉密尔顿抑郁量表（HAMD）和神经功能缺损评分（NIHSS）进行评定,并观察并发症情况。结果两组患者治疗后1个月、3个月和6个月的HAMD评分和NIHSS评分较治疗前明显下降（P〈0．05或〈0．01）,对照组治疗后1个月NIHSS评分差异无统计学意义（P〉0．05）,且治疗组评分明显低于对照组（P〈O．05或〈0．01）。治疗3个月后,治疗组抑郁康复痊愈率和总有效率分别为36．6％和95．1％,明显高于对照组的15．0％、72．5％;治疗组神经功能康复痊愈率和总有效率分别为24．4％和92．7％,明显高于对照组的7．5％、75．0％,差异有统计学意义（P〈0．05）。无严重并发症病例。结论脑卒中后抗抑郁治疗有利于患者神经功能恢复,改善患者的抑郁症状。
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| 关 键 词： | 中风 抑郁 氟西汀 |
Clinical significance on recovery of nerves functional rehabilitation under treatment of post-stroke depression |
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| WU Cai-tang. Clinical significance on recovery of nerves functional rehabilitation under treatment of post-stroke depression[J]. Clinical Focus, 2009, 24(4): 310-313 |
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| Authors: | WU Cai-tang |
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| Affiliation: | WU Cai-tang Department of Neurology,Xinglin District of the First Hospital of Xiamen,Xiamen 361022,China |
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| Abstract: | Objective To explore the clinical significance on the recovery of nerves functional rehabilitation under the treatment of post-stroke depression(PSD).Methods Eighty-one cases with post-stroke depression were selected and divided into study group(41 cases,men 23 vs wemen 18) and control group (40 cases,men 21 vs wemen 19).For control group,anticoagulation,thrombolysis,anhydration,diuresis,depressurization,lower blood sugar and nutrition cranial nerves were conventionally given.And for study group,the fluoxet... |
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| Keywords: | stroke depression fluoxetine |
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