北京地区健康志愿者胫骨超声速率的测定及其分析

目的：初步建立北京健康人群的胫骨骨超声速率（Tibia speed of sound,Tibia SOS)的正常参考值。方法：用以色列Myriad公司生产的Sound Scan2000型胫骨超声测定仪,对951名北京地区的健康志愿者（男性461名,女性490名）进行胫骨SOS的测定,按不同性别,以十岁为界,80岁以上合并为1组,男女各分7组。结果：男女胫骨SOS在30－39岁年龄组达到峰值,之后男女均开始下降,50岁以后女性下降速度比男性快。妇女绝经前后的胫骨SOS差异显著;胫骨SOS随绝经年限的增加而下降,但下降速度是非线性的,可分为：快速下降期、稳定期和再下降期。结论：胫骨SOS的测定是诊断骨眩松症的一种可行的方法。

Study of normal range of speed of sound in tibia in Beijing area

OBJECTIVE: To study the normal reference value of adult tibial speed of sound (tibia SOS) in Beijing region. METHODS: 951 normal volunteers (male/female = 461/490) were included in this study. Speed of sound were measured in the middle of tibia by ultrasound scan (Sound Scan 2000, Myrid, Isereal). According to their gender and age, all subjects were divided into different subgroup by 10 year-age period. RESULTS: The peak value of SOS presented in 30-39 years period in both male and female. The peak value was higher in males than in females. After reach the peak value, the tibial SOS begin to decline. The decreasing rate was fast in SOS were found at 50-59 period in female and over 50-59 years old in male. The tibia values of SOS of postmenopausal was obviously lower than that of premenopausal women. The relationship of menopausal duration and the values if tibial SOS was found to be a non-linear curve, which included 3 stages: the quick decrease, stabilization and further decrease. CONCLUSION: The tibia values of SOS provides a kind of meaningful diagnostic criteria of osteoporosis.