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| Study on Metabolites of Aconitum Alkaloids in Human Urine | |
| 引用本文： | ForMaster‘sDegree:SUNYing Supervisor:Prof.ZHANGHong-gui ZHONGda-fang ZHANGHan-qi. Study on Metabolites of Aconitum Alkaloids in Human Urine[J]. 中国药学, 2003, 12(1): 54-55 |
| 作者姓名： | ForMaster‘sDegree:SUNYing Supervisor:Prof.ZHANGHong-gui ZHONGda-fang ZHANGHan-qi |
| 作者单位： | [1]ChangchunMedicalCollege,Changchun130031 [2]DepartmentofAnalyticalChemistry,CollegeofCHemistry,JilinUniversity,Changchun130023 |
| 基金项目： | Thisresearchproject (3 9870 874and 3 993 0 180)wassupportedbytheNationalNaturalScienceFoundationofChina |
| 摘 要： | TheaconitebelongstoplantsofgenusAconituminfamilyofRanunculaceaandhavenotableclinicalfunctionsintreatingrheumaticarthritis ,heartfailure ,etc .However,accidentsofaconitine(fromaconite)poisoningfrequentlyoccurtomanypeopletakingtheseherbs .Theplantsofthisfamilycontainaconitine ,mesaconitine ,hypaconitineandotheraco nitumalkaloids .Theyarehighlytoxic ,andtheirtreatmentdoseapproachestothetoxicdoseorlethaldose .Duringtheperiodfrom 1989- 1995 ,morethan 30casesofpoisoningcausedbyaconitineinsometradit… |
| 关 键 词： | 乌头 乌头碱 代谢物 药物中毒 尿液检验 LC－MS |
Study on Metabolites of Aconitum Alkaloids in Human Urine |
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| SUN Ying,ZHANG Hong-gui,ZHONG Da-fang,ZHANG Han-qi. Study on Metabolites of Aconitum Alkaloids in Human Urine[J]. Journal of Chinese Pharmaceutical Sciences, 2003, 12(1): 54-55 | |
| Authors: | SUN Ying ZHANG Hong-gui ZHONG Da-fang ZHANG Han-qi |
| Abstract: | The aconite belongs to plants of genus Aconitum in family of Ranunculacea and have notable clinical functions intreating rheumatic arthritis, heart failure, etc. However, accidents of aconitine(from aconite) poisoning frequently occurto many people taking these herbs. |
| Keywords: | aconite metabolites poisoning aconitine LC-MS |
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