重组汤对腮腺炎病毒作用的体外实验研究

目的 进一步求证重组汤对腮腺炎病毒体外灭活作用的特异性。方法 采用组织细胞培养技术，对腮腺炎病毒、单纯疱疹病毒(I、II型)、风疹病毒、巨细胞病毒、带状疱疹病毒、流感病毒、副流感病毒、腺病毒、呼吸道合胞病毒进行培养的过程中，给以实验药物攻击，观察病毒被灭活的过程。结果 实验药物在体外对腮腺炎病毒具有显著的抑制和杀伤作用，而对单纯疱疹病毒(I、II型)、风疹病毒、巨细胞病毒、带状疱疹病毒、流感病毒、副流感病毒、腺病毒、呼吸道合胞病毒无抑制作用。若增大实验药物剂量则对细胞本身的增殖生长有很大的副作用。结论 重组汤在体外实验中，对腮腺炎病毒具有抑制和杀伤作用的特异性。

Experimental study on effect of recombined decoction on mumps virus

OBJECTIVE: To evaluate possible inactivating effect of recombined decoction in on mumps virus. METHODS: By adopting tissue cell culturing technology, a group of viruses including the mumps virus, herpes simplex virus (type I, II), rubella virus, cytomegalovirus (CMV), herpes zoster virus, influenza virus, parainfluenza virus, adeno viruses, respiratory syneytial virus (RSV) were cultured. The cells infected with the viruses were treated with the decoction. RESULTS: The decoction showed remarkable inhibitory and killing effects on the mumps virus while had no obvious inhibitory and killing effects on host's cells, herpes simplex virus (type I, II), rubella virus, cytomegalovirus (CMV), herpes zoster virus, influenza virus, parainfluenza virus, adeno viruses, respiratory syneytial virus (RSV). CONCLUSIONS: The decoction had obvious inhibitory and killing effects on mumps virus during single layer cells culture.