|
|||||
|
|
| 产超广谱β-内酰胺酶肺炎克雷伯菌β-内酰胺酶与Ⅰ类整合酶基因研究 | |
| 引用本文： | 徐卫东,徐红星,陈昭华,吴元健,糜祖煌. 产超广谱β-内酰胺酶肺炎克雷伯菌β-内酰胺酶与Ⅰ类整合酶基因研究[J]. 中华医院感染学杂志, 2007, 17(11): 1342-1344 |
| 作者姓名： | 徐卫东 徐红星 陈昭华 吴元健 糜祖煌 |
| 作者单位： | 1. 南京医科大学附属苏州市立医院,江苏,苏州,215002 2. 无锡市克隆遗传技术研究所,江苏,无锡,214026 |
| 摘 要： | 目的了解产超广谱β-内酰胺酶(ESBLs)肺炎克雷伯菌中β-内酰胺酶和Ⅰ类整合酶(intⅠ1)基因存在状况。方法对35株肺炎克雷伯菌,采用聚合酶链反应(PCR)检测TEM、SHV、OKP、CTX-M-1群、CTX-M-2群、CTX-M-9群、GES、PER、VEB、OXA-10、ACT-1、LEN、DHAi、ntⅠ1基因。结果35株肺炎克雷伯菌中检出β-内酰胺酶基因22株,阳性率62.9%;intⅠ1阳性21株,阳性率60.0%。结论产ESBLs肺炎克雷伯菌β-内酰胺酶基因和intⅠ1基因携带率高。 |
| 关 键 词： | 肺炎克雷伯菌 β-内酰胺酶基因 Ⅰ类整合酶基因 |
| 文章编号： | 1005-4529（2007）11-1342-03 |
| 收稿时间： | 2007-02-20 |
| 修稿时间： | 2007-06-18 |
Beta-lactamase Gene and intⅠ1 Gene in ESBLs-producing Klebsiella pneumoniae |
|
| XU Wei-dong,XU Hong-xing,CHEN Zhao-hua,WU Yuan-jian,MI Zu-huang. Beta-lactamase Gene and intⅠ1 Gene in ESBLs-producing Klebsiella pneumoniae[J]. Chinese Journal of Nosocomiology, 2007, 17(11): 1342-1344 | |
| Authors: | XU Wei-dong XU Hong-xing CHEN Zhao-hua WU Yuan-jian MI Zu-huang |
| Affiliation: | Suzhou Municipal Hospital Affiliated to Nanjing Medical University, Suzhou, Jiangsu 215002, China |
| Abstract: | OBJECTIVE To investigate the beta-lactamase gene and int I 1 gene in ESBLs-producing Klebsiella pneumoniae. METHODS Beta-lactamase gene and int I 1 gene were analyzed by PCR. RESULTS The positive rates of TEM, SHV, OKP, CTX-M-lgroup, CTX-M-2group, CTX-M-ggroup, GES, PER, VEB, OXA-10, ACT-l, LEN, DHA, and int I 1 were 51.4%, 0%, 0%, 17. 1%, 0%, 11.4%, 0%, 0%, 0%, 0%, 0%, 5.7%, 17.1%, and 60%, respectively. Beta-lactamase gene was found in 62. 9%, int I 1 gene was found in 60%. CONCLUSIONS There are very high positive percentages of beta-lactamase gene and int I 1 gene in ESBLs- producing K. pneumoniae. |
| Keywords: | Klebsiella pneumoniae Beta-lactamase gene int I 1 gene |
| 本文献已被 CNKI 维普 万方数据 等数据库收录！ | |