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| C20型二萜生物碱的构效关系研究进展 | |
| 引用本文： | 李瑞阳,冯 锋,刘静涵. C20型二萜生物碱的构效关系研究进展[J]. 海峡药学, 2013, 0(12): 1-4 |
| 作者姓名： | 李瑞阳 冯 锋 刘静涵 |
| 作者单位： | 中国药科大学天然药物化学教研室,南京210009 |
| 摘 要： | C20型二萜生物碱是一类结构复杂、活性多样的化合物,它们的结构和活性之间有着密切的关系.本文综述了C20型二萜生物碱的结构特征与活性间的构效关系,为结构修饰提供依据以更快得到高效低毒的化合物. |
| 关 键 词： | C20型二萜生物碱 药理作用 构效关系 |
Advance in studies on structure-activity relationships of C20-Diterpenoid alkaloids |
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| LI Rui-yang,FENG Feng,LIU Jing-han. Advance in studies on structure-activity relationships of C20-Diterpenoid alkaloids[J]. Strait Pharmaceutical Journal, 2013, 0(12): 1-4 | |
| Authors: | LI Rui-yang FENG Feng LIU Jing-han |
| Affiliation: | ( Department of Natural Medicinal Chemistry, China Pharmaceutical University, Nanjing 210009, China) |
| Abstract: | C20-Diterpenoid alkaloids are compounds with diverse pharmacological activities and structural complexity. There is a close relationship between its structure and activity. This review deals with the advance in studies on structure-activity relationships of C20-Diterpenoid alkaloids, which can provide some value information for the proper structural modification to find high-efficient and low toxicity compound efficiently. |
| Keywords: | C20-Diterpenoid alkaloids Pharmacological activity Structure-activity relationship |
| 本文献已被 CNKI 维普 等数据库收录！ | |