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Bacillus cereus infections among oncology patients at a children's hospital
Authors:Christenson J C  Byington C  Korgenski E K  Adderson E E  Bruggers C  Adams R H  Jenkins E  Hohmann S  Carroll K  Daly J A  Pavia A T
Affiliation:University of Utah School of Medicine, Department of Pediatrics, Divisions of Infectious Diseases, Salt Lake City 84132, USA.
Abstract:
BACKGROUND: Bacillus cereus can cause severe infections in immunocompromised persons. METHODS: We report 3 cases of bacteremia/septicemia (1 fatal) among oncology patients in a children's hospital. Because all cases occurred during a 10-day period, a common source outbreak was suspected. An epidemiologic investigation was performed. Molecular comparison of patient and environmental isolates was performed by using pulsed-field gel electrophoresis. RESULTS: After an extensive investigation, no common hospital source could be found. Pulsed-field gel electrophoresis proved that the isolates were not related. CONCLUSION: Sporadic infections in immunocompromised persons do occur and can be associated with significant morbidity.
Keywords:
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