冠心病患者冠脉支架植入前后Hs-CRP含量的变化及意义

目的 探讨冠心病患者冠脉支架植入前后血清C反应蛋白水平的变化及意义.方法 选择行冠脉支架植入术的冠心病患者40例,于支架植入术前及术后分别测定C反应蛋白(CRP)含量.比较PCI术前后CRP水平的变化.结果 冠脉支架植入术前血清CRP平均浓度为(7.86±3.58)mg/L,术后平均浓度为(13.91±3.61)mg/L,两者比较差异有显著性意义(P＜0.01).结论 C反应蛋白水平在冠心病患者冠脉支架植入术后较术前有显著升高,C反应蛋白水平可能对防治冠心病介入治疗术后并发症具有重要的意义.

The change and significance of C-reactive protein concentration in patients with coronary heart disease before and after percutaneous coronsry intervention

Objective To detect the concentration of C-reactive protein in patients with coronary heart disease before and after percutaneous coronary intervention (PCI).Methods Forty patients with coronary heart disease that treated with PCI were enrolled.The serum concentration of C-reactive protein (CRP) was analyzed before and after the PCI.Results After PCI,the concentration of CRP were significantly increased compared with that before PCI[(13.91±3.61 ) mg/L versus ( 7.86±3.58 )mg/L,P＜0.01].Conclusion The concentrations of CRP in patients with coronary heart disease were significantly increased after PCI.The level of serum Hs-CRP may reflect inflammatory state of atherosclerosis plaque and it may be important to the prevention and treatment of complications after PCI.