In vitro stimulation of cyclic-AMP production in Rana catesbeiana ovaries by homologous gonadotropins. |
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| Authors: | J Gavaud P Licht H Papkoff |
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| Affiliation: | 1. Hormone Research Laboratory, University of California, San Francisco, California 94143 USA;2. Reproductive Endocrinology Center, University of California, San Francisco, California 94143 USA;3. Department of Zoology, University of California, Berkeley, California 94720 USA |
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| Abstract: | In vitro effects of purified Rana LH and FSH on cyclic AMP accumulation were examined in ovaries of immature and mature bullfrog, Rana catesbeiana, at different states of the sexual cycle. Rana FSH was active with clear dose dependency only in immature ovaries but was less potent than Rana LH. Mature females did not respond to Rana FSH. Rana LH always increased the cAMP accumulation in mature females but the response was lowest with prespawning and postspawning females. |
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