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血清CA199与CEA检测对结直肠癌的诊断价值
引用本文:庄珊珊,陈炯玉,方裕森,游颜杰. 血清CA199与CEA检测对结直肠癌的诊断价值[J]. 陕西肿瘤医学, 2010, 18(7): 1359-1361
作者姓名:庄珊珊  陈炯玉  方裕森  游颜杰
作者单位:[1]汕头大学医学院附属肿瘤医院,广东汕头515041 [2]汕头大学医学院,广东汕头515041
摘    要:目的:研究肿瘤相关糖类抗原199(CA199)与癌胚抗原(CEA)检测对结直肠癌的诊断价值。方法:采用电化学发光方法检测44例结直肠癌患者与19例正常人血清中CA199与CEA的水平并进行统计学分析。结果:结直肠癌患者血清中CA199和CEA水平明显高于正常对照组良性对照组(P〈0.05);治疗后CA199与CEA含量与治疗前相比显著降低(P〈0.05)。结论:CA199与CEA检测结对结直肠癌临床诊断与疗效评价有一定的意义。

关 键 词:结直肠癌  CA199  CEA

Diagnostic value of CA199 and CEA in serum of patients with colorectal carcinoma
Affiliation:ZHUANG Shan - shan , CHEN Jiong - yu, FANG Yu - sen , YOU Yan- jie (1.Cancer Hospital of Shantou University Medical College, Shantou 515041, China;2.Medical College of Shantou University, Shantou 515041, China.)
Abstract:Objective:To investigate the diagnostic value of CA199 and CEA in serum of patients with colorectal carcinoma. Methods:Serum levels of CA199 and CEA were measured by electrochemiluminescenee assay in 19 normal adults and 44 patients with colorectal carcinoma. Results:The levels of CA199 and CEA in patients with colorectal carcinoma were obviously higher than those in control group ( P 〈 0. 05 ), while they were significantly decreased after treatment (P 〈 0.05 ). Conclusion:The detection of CEA and CA199 has a notable value in diagnosis and therapeutic evaluation for patients with coloreetal carcinoma.
Keywords:colorectal carcinoma  CA199  CEA
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