Rod and Cone a-Waves in Central Retinal Vein Occlusion |
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| Authors: | Naoyuki Tanimoto Tomoaki Usui Mikio Ichibe Mineo Takagi Keiko Suzuki Shigeru Hasegawa Haruki Abe |
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| Affiliation: | (1) Division of Ophthalmology and Visual Science, Graduate School of Medical and Dental Sciences, Niigata University, Niigata, Japan;(2) Division of Ophthalmology and Visual Science, Graduate School of Medical and Dental Sciences, Niigata University, 1-757 Asahimachi, Niigata 951-8510, Japan |
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| Abstract: | ![]()
Purpose To evaluate rod and cone a-waves in cases with unilateral central retinal vein occlusion (CRVO). Methods Scotopic and photopic flash electroretinograms (ERGs) were recorded in seven patients aged 54–84 with unilateral hemorrhagic CRVO. Rod and cone a-waves were analyzed using photoreceptor models, and Rm p3 (maximum a-wave amplitude) and S (sensitivity) were calculated. Results Decreased rod log?S was found in all seven cases, and decreased cone log?S was found in five cases. In only one case, rod log?S in the fellow eye was decreased. The alterations in rod and cone log Rm p3 were smaller than those in rod and cone log?S. Of three cases in which ERGs could be recorded again after a certain follow-up period, rod log?S and cone logS became larger in two cases and smaller in one case. Conclusions The change in the phototransduction cascade was confirmed not only in rods but also in cones in five of our seven cases of CRVO. The ERG findings might reflect the functional change in the photoreceptor layer after the onset of CRVO. Jpn J Ophthalmol 2005;49:402–410 © Japanese Ophthalmological Society 2005 |
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| Keywords: | central retinal vein occlusion cone electroretinogram phototransduction rod |
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