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Ventricular Tachycardia in Acute Fulminant Myocarditis: Medical Management and Follow-up
Authors:J. R. Sharma  S. Sathanandam  S. P. Rao  S. Acharya  V. Flood
Affiliation:(1) Division of Pediatric Cardiology, Hematology and Intensive Care, Department of Pediatrics, The Children’s Hospital at Downstate/State University of New York, 450, Clarkson Avenue, Brooklyn, NY 11203, USA;(2) Division of Hematology/Oncology, Department of Pediatrics, The New York Presbyterian/The University Hospital of Cornell, 525 East 68th Street, New York, NY 10021, USA;(3) Division of Hematology/Oncology, Doernbecher Children’s Hospital, Oregon Health and Science University, Portland, OR 97239, USA
Abstract:
The combination of ventricular tachycardia (VT) and severe left ventricular dysfunction presents a serious challenge in management of acute fulminant myocarditis (AFM). We report a case of a 17-month-old girl with AFM, presented with hypotension and VT, successfully treated with respiratory and inotropic support, high-dose intravenous immunoglobulin, and amiodarone. The myocardial function improved significantly within 2 weeks of treatment. The clinical course was complicated by significant amiodarone-induced hepatotoxicity, disseminated intravascular coagulation, and deep-vein thrombosis. She was later diagnosed with congenital dysfibrinogenemia and treated with chronic Lovenox therapy.
Keywords:Ventricular ectopy  Fulminant myocarditis  Amiodarone  Intravenous immunoglobulins
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