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ezrin在乳腺癌中的表达及其临床意义
引用本文:李文广,张燕妮,颜海,凌黎,李京微,姜海英,李艳芳. ezrin在乳腺癌中的表达及其临床意义[J]. 中国综合临床, 2002, 25(1): 699-701. DOI: 10.3760/cma.j.issn.1008-6315.2009.07.010
作者姓名:李文广  张燕妮  颜海  凌黎  李京微  姜海英  李艳芳
作者单位:江苏省徐州市肿瘤医院肿瘤内科,221005;江苏省徐州市肿瘤医院普外科,221005;江苏省徐州市肿瘤医院病理科,221005;
基金项目:徐州市卫生局科技计划项目
摘    要:
Objective To study the expression and clinical significance of ezrin in breast carcinoma. Methods Immunohistuchemieal staining(S-P) was used to detect the expression of ezrin in 63 cases of breast car-cinoma samples. Results Among these 63 samples,the total expression rates of ezrin were 55.56% (35/63). With the increasing of axillary lymph nodes metastasis and clinical staging,the rates of expressing of ezrin elevated (P<0.05),which was remarkably lower in patients whose disease-free survival(DFS) was > 5 years,or those whose DFS≤5 years or died within five years(P<0.05) ,but the expression of ezrin was not correlated with tumor size,age and menopausal status (P>0.05). Conclusion The expression of ezrin may contribute to prognostic e-valuation for breast carcinoma.

关 键 词:乳腺癌   免疫组化   预后   

Expression and clinical significance of ezrin in breast carcinomas
Li Wen-guang,Zhang Yan-ni,Yan Hai,Ling Li,Li Jing-Wei,Jiang Hai-ying,Li Yen-fang. Expression and clinical significance of ezrin in breast carcinomas[J]. Clinical Medicine of China, 2002, 25(1): 699-701. DOI: 10.3760/cma.j.issn.1008-6315.2009.07.010
Authors:Li Wen-guang  Zhang Yan-ni  Yan Hai  Ling Li  Li Jing-Wei  Jiang Hai-ying  Li Yen-fang
Abstract:
Keywords:ezrinEzrinBreast carcinomaImmunohistochemistryPrognosis
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