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糖尿病家族史对糖尿病发病及相关危险因素的影响
引用本文:娄能俊,杜书玉,辛颖,廖琳,董建军.糖尿病家族史对糖尿病发病及相关危险因素的影响[J].山东大学学报(医学版),2010,48(2):4.
作者姓名:娄能俊  杜书玉  辛颖  廖琳  董建军
作者单位:1. 山东大学第二医院内分泌科,济南,250033
2. 山东大学齐鲁医院高新区医院,济南,250101
3. 山东大学附属省立医院内分泌科,济南,250021
4. 山东大学齐鲁医院内分泌科,济南,250012
基金项目:山东省科技厅课题(963000052)
摘    要:目的 探讨糖尿病家族史对糖尿病发病及相关危险因素的影响.方法 在糖尿病流行病学调查基础上,根据有无糖尿病家族史将人群分为有糖尿病家族史者(A组,n=1 145)、无糖尿病家族史者(B组,n=4 203)两组.分别对两组人群的糖尿病和糖耐量异常(IGT)的患病率进行统计,并采用非条件logistic回归分析筛选糖尿病的危险因素,根据危险因素的回归系数β值确定不同变量的积分值,以累计积分值的大小判断个体患病的危险性.结果 A组糖尿病患病率为9.9%,IGT患病率为20.1%;B组糖尿病患病率为2.1%,IGT患病率为9.9%,趋势性X~2检验具有统计学意义(P<0.001).结论 有糖尿病家族史的人群糖尿病患病率明显高于普通人群,肥胖成为主要的可控危险因素,对其进行干预有望预防或延缓糖尿病的发生发展.

关 键 词:糖尿病  家族史  危险因素
收稿时间:2009-07-19

Contribution of diabetes family history to the morbidity rate of diabetes and other risk factors
LOU Neng-jun,DU Shu-yu,XIN Ying,LIAO Lin,DONG Jian-jun.Contribution of diabetes family history to the morbidity rate of diabetes and other risk factors[J].Journal of Shandong University:Health Sciences,2010,48(2):4.
Authors:LOU Neng-jun  DU Shu-yu  XIN Ying  LIAO Lin  DONG Jian-jun
Institution:LOU Neng-jun1,DU Shu-yu2,XIN Ying3,LIAO Lin3,DONG Jian-jun4(1.Department of Endocrinology,the Second Hospital of Sh,ong University,Jinan 250033,China,2.Qilu Hospital at Development Zone of Sh,ong University,Jinan 250101,3.Department of Endocrinology,Provincial Hospital Affiliated to Sh,ong University,Jinan 250021,4.Department of Endocrinology,Qilu Hospital of Sh,ong University,Jinan 250012,China)
Abstract:Objective To investigate the contribution of diabetes family history to the morbidity rate of diabetes and other risk factors.Methods Based on an epidemiological survey of diabetes mel1itus,a target population with or without family history of diabetes was evaluated to see the influence of family history to the morbidity rate of diabetes and other risk factors.The population enrolled was divided into two groups: group A(n=1145)had a family history of diabetes,and group B(n=4203)did not.The morbidity rate of...
Keywords:Diabetes mellitus  Family history of diabetes  Risk factors  
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