| C－erbB－2癌基因蛋白和PCNA在大肠癌组织中的表达及其意义 |
| |
| 引用本文： | 文继舫,曾庆富,颜亚晖,沈明.C－erbB－2癌基因蛋白和PCNA在大肠癌组织中的表达及其意义[J].中南大学学报(医学版),1996(4). |
| |
| 作者姓名： | 文继舫 曾庆富 颜亚晖 沈明 |
| |
| 作者单位： | Department of Pathalogy，Hunan Medical University |
| |
| 摘 要： | 应用免疫组化Ｓ－Ｐ法检测了１１１例大肠癌及５７例癌旁粘膜组织的Ｃ－ｅｒｂＢ－２癌基因蛋白和ＰＣＮＡ表达状况。结果表明：①大肠癌组织Ｃ－ｅｒｂＢ－２癌基因蛋白和ＰＣＮＡ阳性表达率分别为４８．６％，７２．１％；癌旁粘膜仅为２８．１％，１４．８％；前者Ｃ－ｅｒｂＢ－２（Ｐ＜０．０５）ｆｏＰＣＮＡ（Ｐ＜０．０１）的表达率显著高于后者。②Ｃ－ｅｒｂＢ－２癌基因蛋白和ＰＣＮＡ阳性率与癌组织分化程度及淋巴结转移有显著相关性（Ｐ＜０．０５）。提示：测定Ｃ－ｅｒｂＢ－２癌基因产物和ＰＣＮＡ，有助于对大肠癌生物学行为的进一步认识及患者预后的分析。
|
| 关 键 词： | 肠肿瘤 癌基因产物类 增殖细胞核抗原 免疫组织化学 |
EXPRESSION OF C-erbB-2 ONCOGENE PROTEIN AND PCNA IN COLORECTAL CANCERS AND THEIR CLINICAL-PATHOLOGICAL SIGNIFICANCE |
| |
| Wen Jifang,Zeng Qingfu,Yan Yahui,Shen Ming.EXPRESSION OF C-erbB-2 ONCOGENE PROTEIN AND PCNA IN COLORECTAL CANCERS AND THEIR CLINICAL-PATHOLOGICAL SIGNIFICANCE[J].Journal of Central South University (Medical Sciences)Journal of Central South University (Medical Sciences),1996(4). |
| |
| Authors: | Wen Jifang Zeng Qingfu Yan Yahui Shen Ming |
| |
| Abstract: | |
| |
| Keywords: | intestinal neoplasms oncogene products proliferating cell nuclear antigen immunohistochernistry |
| 本文献已被 CNKI 等数据库收录！ |
