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Expression and transcriptional regulation of ABC transporters and cytochromes P450 in hCMEC/D3 human cerebral microvascular endothelial cells |
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| Authors: | Sandrine Dauchy Florence Miller Pierre-Olivier Couraud Richard J. Weaver Ignacio-Andres Romero Isabelle De Waziers |
| Affiliation: | a Neuropsychopharmacologie des addictions (CNRS UMR 7157), Université Paris Descartes, Faculté de Pharmacie, Paris, France b Inserm U705, Neuropsychopharmacologie des addictions, Paris, France c Inserm, U567, Paris, France d Institut Cochin, Université Paris Descartes, CNRS (UMR 8104), Paris, France e Centre for Biopharmacy Research, Servier Research & Development Ltd., Wexham, UK f Department of Medicine, Weill Medical College, New York, NY, USA g Department of Biological Sciences, Open University, Milton Keynes, UK h Inserm UMR-S775, Paris, France |
| Abstract: | |
| Keywords: | ABC, ATP-binding cassette AhR, aryl hydrocarbon receptor BBB, blood-brain barrier BCRP, breast cancer resistance protein CAR, constitutive androstane receptor CNS, central nervous system CYP, cytochromes P450 MDR, multidrug resistance MRP, multidrug resistance-associated protein P-gp, P-glycoprotein PXR, pregnane xenobiotic receptor |
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