| 96例服刑AIDS患者高效抗逆转录病毒治疗临床观察 |
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| 引用本文： | 杨星,杨珂露,罗翠.96例服刑AIDS患者高效抗逆转录病毒治疗临床观察[J].传染病信息,2009,22(6):356-359. |
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| 作者姓名： | 杨星 杨珂露 罗翠 |
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| 作者单位： | 云南省监狱管理局中心医院,昆明,650216 |
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| 基金项目： | 云南省第四轮全球基金/中英艾滋病项目资助 |
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| 摘 要： | 目的探索在监管场所应用高效抗逆转录病毒治疗（highly active antiretroviral therapy，HAART）服刑人员AIDS的临床疗效、安全性及管理特点。方法对2007年2月-2009年3月收治的应用HAART疗程满6个月以上的96例服刑AIDS患者资料进行分析，评价疗效及安全性。结果所有患者临床症状有不同程度的改善，无严重不良事件发生，服药依从性为100％。治疗6个月时93．0％的患者病毒载量（viral load，VL）〈50copies／ml，CD4＋T淋巴细胞计数较治疗前平均增加108．8／mm^3；治疗12个月时95．8％的患者VL〈50copies／ml，CD4＋T淋巴细胞计数较治疗前平均增加119．9／mm^3。结论在监管场所对服刑AIDS患者施行HAART治疗，可使患者血中CD4＋T淋巴细胞计数显著升高，VL显著下降。对服刑AIDS患者严格管理、规范治疗、严密监测及100％服药依从性是治疗成功的关键。
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| 关 键 词： | AIDS 服刑人员 高效抗逆转录病毒治疗 |
Highly active antiretroviral therapy of 96 imprisoned persons suffering from AIDS |
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| Yang Xing,Yang Kelu,Luo Cui.Highly active antiretroviral therapy of 96 imprisoned persons suffering from AIDS[J].Infectious Disease Information,2009,22(6):356-359. |
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| Authors: | Yang Xing Yang Kelu Luo Cui |
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| Institution: | Yang Xing,Yang Kelu,Luo Cui Central Hospital of Yunnan Provincial Bureau of Prison Administration,Kunming 650216,China |
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| Abstract: | Objective To investigate clinical efficacy and safety of highly active antiretroviral therapy(HAART) undergorein prisons on imprisoned persons suffering from AIDS and explore the prison administration of such persons. Methods Clinical data of 96 imprisoned persons suffering from AIDS,who received HAART for more than 6 months from Feb. 2007 to Mar. 2009,were analyzed and the ther-apeutic efficacy and safety were evaluated. Results Clinical symptoms had been alleviated more or less in all the AIDS patients wi... |
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| Keywords: | AIDS |
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