磁共振灌注成像在脑肿瘤中的初步应用

目的本研究旨在初步评价脑肿瘤磁共振灌注成像（PWI）的成像方法及其临床应用价值。方法对钙例经病理证实的脑肿瘤患者，其中低级别胶质瘤13例，高级别胶质瘤23例，脑膜瘤8例，淋巴瘤4例，行MR灌注成像及常规MRI检查。由灌注数据获取脑血流容积（CBV）图，计算出相对脑血流容积（rCBV）值。结果高级别胶质瘤和脑膜瘤为高灌注，低级别胶质瘤和淋巴瘤为低灌注，高、低灌注组间rCBV值有显著性差异，而高灌注肿瘤之间和低灌注肿瘤之间rCBV值无显著性差异。结论PWI在脑肿瘤的鉴别诊断方面有一定价值。

Preliminary application of MR perfusion imaging in brain tumors

Objective The goal of our study is to evaluate methods of MR perfusion weighted imaging(PWI)in brain neoplasms and its clinical application.Methods This study involved 48 patients(23 high-grade gliomas,13 low-grade gliomas,8 meningiomas and 4 lymphomas) who were identified as having histopathologically proven gliomas.MR perfusion imaging and MR conventional imaging were performed preoperatively in them.The perfusion dada were deconvoluted to get a color map of CBV.The rCBV ratio of each lesion was calculated.Results The rCBV ratios of high-grade gliomas and meningiomas were statistically different from those of low-grade gliomas and lymphomas,while there was no significant difference between high perfusion tumors and between low perfusion tumors.Conclusion MR perfusion imaging is useful in the differentiation of brain tumors.