Role of thymidylate synthase and dihydropyrimidine dehydrogenase mRNA in intrahepatic cholangiocarcinoma |
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| Authors: | Yuji Morine Mitsuo Shimada Tohru Utsunomiya Satoru Imura Tetsuya Ikemoto Jun Hanaka Mami Kanamoto Nobuhiro Kurita Hidenori Miyake |
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| Affiliation: | (1) Department of Surgery, Institute of Health Biosciences, University of Tokushima Graduate School, 3-18-15 Kuramoto-cho, Tokushima 770-8503, Japan |
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| Abstract: | ![]()
Purpose Thymidylate synthase (TS) and dihydropyrimidine dehydrogenase (DPD) are important enzymes in the metabolism of 5-fluorouracil and possible predictive markers. We conducted this study to clarify if TS and DPD gene expressions are a prognostic indicator for intrahepatic cholangiocarcinoma (IHCC). |
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