Lung injury induced by the pulmonary instillation of povidone-iodine in rats |
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Authors: | Soon Ho Cheong Young Il Yang Min Young Choi Myoung Hun Kim Kwang Rae Cho Se Hun Lim Jeong Han Lee Kun Moo Lee Sung Ho Moon |
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Affiliation: | (1) Department of Anesthesiology, Paik Hospital, Inje University, Gaegumdong, Jingu, Busan, Korea;(2) Department of Pathology, Paik Hospital, Inje University, Gaegumdong, Jingu, Busan, Korea;(3) Paik Institute for Clinical Research, Inje University, Gaegumdong, Jingu, Busan, Korea |
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Abstract: | ![]()
Purpose Povidone-iodine (polyvinylpyrrolidone iodine, PI), which is commonly used as a pre- and postoperative oral antiseptic, has been reported to cause pneumonia secondary to its pulmonary aspiration. Because no studies have yet investigated the underlying mechanisms of PI-induced pneumonia, we conducted an animal study to analyze the effect of PI on the lung following its pulmonary instillation. |
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