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Lung injury induced by the pulmonary instillation of povidone-iodine in rats
Authors:Soon Ho Cheong  Young Il Yang  Min Young Choi  Myoung Hun Kim  Kwang Rae Cho  Se Hun Lim  Jeong Han Lee  Kun Moo Lee  Sung Ho Moon
Affiliation:(1) Department of Anesthesiology, Paik Hospital, Inje University, Gaegumdong, Jingu, Busan, Korea;(2) Department of Pathology, Paik Hospital, Inje University, Gaegumdong, Jingu, Busan, Korea;(3) Paik Institute for Clinical Research, Inje University, Gaegumdong, Jingu, Busan, Korea
Abstract:

Purpose  

Povidone-iodine (polyvinylpyrrolidone iodine, PI), which is commonly used as a pre- and postoperative oral antiseptic, has been reported to cause pneumonia secondary to its pulmonary aspiration. Because no studies have yet investigated the underlying mechanisms of PI-induced pneumonia, we conducted an animal study to analyze the effect of PI on the lung following its pulmonary instillation.
Keywords:
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