双源CT灌注参数评估胃癌生物学行为的诊断试验研究

目的：探讨双源CT灌注参数BV、BF、Patlak P对胃癌生物学行为的评估价值。方法：使用双源CT对98例胃癌病人行灌注扫描，获得BF、BV、Patlak P值并以其对胃癌的生物学行为进行评估，以确定该灌注参数的评估价值。结果：双源CT灌注参数BF对无远隔转移组的诊断灵敏度为72.13%，特异度为64.52%，阳性预测值为81.67%，阴性预测值为52.63%，正确率为70.41%。BV对无远隔转移组的诊断灵敏度为68.66%，特异度为51.61%，阳性预测值为75.41%，阴性预测值为43.24%，正确率为63.27%。BV对癌组织局限于浆膜内的诊断灵敏度为60.00%，特异度为69.57%，阳性预测值为86.54%，阴性预测值为34.78%，正确率为62.24%。Patlak P值对癌组织局限于胃壁肌层内的诊断灵敏度为61.54%，特异度为75.86%，阳性预测值为69.57%，阴性预测值为68.75%，正确率为69.09%。Patlak P对癌组织突破浆膜的诊断诊断灵敏度为14.29%，特异度为69.23%，阳性预测值为60%，阴性预测值为20%，正确率为27.27%。结论：双源CT灌注参数BF、BV、Patlak P能够对胃癌的生物学行为进行评估，但仍有一定的局限性。

The research of dual source CT perfusion parameter in biological behavior of gastric carcinoma

Objective: To investigate the value of dual source CT perfusion imaging parameters,including blood volume(BV),blood flow(BF),and Patlak P value in evaluating the biological behavior of gastric carcinoma.Methods: Dual source CT perfusion imaging was performed in 98 patients of gastric carcinoma.The BV,BF,Patlak P value were obtained to study the relationship between the parameters of perfusion and the biological behavior in gastric cancer,and estimate the value of parameters.Results: The BF could predict gas...