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头孢他啶粉针与常用输液配伍的稳定性考察
引用本文:蔡冬明,康敏. 头孢他啶粉针与常用输液配伍的稳定性考察[J]. 药学与临床研究, 2000, 0(3)
作者姓名:蔡冬明  康敏
作者单位:苏州医学院附属第一医院,苏州市中医院 苏州 215006,苏州 215006
摘    要:
本实验考察了三个不同厂家生产的头孢他啶粉针在5%葡萄糖、5%葡萄糖氯化钠和10%葡萄糖注射液中的稳定性,并采用高效液相色谱法测定头孢他啶含量。结果表明:在35℃条件下,头孢他啶在三种输液中24 h内稳定性较好,含量降低<3%。不同厂家的头孢他啶在输液中的稳定性没有明显差异。这为临床配伍使用头孢他啶提供了实验依据。

关 键 词:头孢他啶  稳定性  高效液相色谱法

Observation on the Stability of three Ceftazidimes after its Combination with Routine Transfusion Solutions
Cai Dongming,Kang MinFirst Affiliated Hospital of Suzhou Medical College. Observation on the Stability of three Ceftazidimes after its Combination with Routine Transfusion Solutions[J]. Pharmacertical and Clinical Research, 2000, 0(3)
Authors:Cai Dongming  Kang MinFirst Affiliated Hospital of Suzhou Medical College
Abstract:
A HPLC method was used to test the concentration change of three Ceftazidimes after its combination with routine transfusion solutions. The result showed that Ceftazidimes was stable when combined with 5 % glucose and sodium chloride, 5 % glucose., 10% glucose solution. The content of three Ceftazidimes change <3% in 24 hours, which was informative to clinical combinational usage.
Keywords:Cef tazidime   stability   HPLC
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