苦碟子化学成分的分离与鉴定

目的对菊科苦荬菜属植物抱茎苦荬菜[Ixeris sonchifolia(Bge.)Hance]的化学成分进行研究。方法运用硅胶﹑聚酰胺柱色谱﹑Sephadex LH-20柱色谱﹑ODS柱色谱、制备HPLC等分离手段进行化学成分的分离纯化,根据理化性质及波谱数据鉴定其结构。结果从苦碟子全草中分离得到4个化合物。分别鉴定为3β-hydroxyolean-12-en-11-one acetate(1)、3,4-dihydroxybenzalacetone(2)、7-O-β-D-glucopyranosyl-luteolin-3'-O-β-D-glucopyranoside(3)、5,7-dihydroxy-4'-methoxy-fla-vone-7-rutinoside(4)。结论这些化合物均为首次从该属植物中分离得到。

Isolation and identification of the constituents from whole plant of Ixeris sonchifolia(Bge.)Hance

Objective To study the chemical constituents of the whole plant of Ixeris sonchifolia (Bge.) Hance. Methods Four compounds were isolated by chromatographies on silica gel column, polyamide, Sephadex LH-20, ODS column, PHPLC and identified on the basis of physico-chemical constant and spectroscopic analysis. Results Four compounds were separated from the extract of Ixeris sonchifolia. On the basis of chemical and spectral methods .These compounds were elucidated as 3β-hydroxyolean-12-en-11-one acetate（1）, 3,4-dihydroxybenzalacetone（2）, 7-O-β-D -glucopyranosyl-luteolin-3'-O-β-D-glucopyranoside（3）, 5,7-dihydroxy-4'-methoxyflavone-7-rutinoside（4）. Conclusion All these compounds were isolated from this genus for the first time .