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鸦胆子化学成分的研究
引用本文:于雅男,李铣.鸦胆子化学成分的研究[J].药学学报,1990,25(5):382-386.
作者姓名:于雅男  李铣
作者单位:沈阳药学院天然药物研究室,沈阳药学院天然药物研究室 沈阳 110015,沈阳 110015
摘    要:继从中药鸦胆子Brucea javanica (L.)Merr的果实中分得一系列具抗肿瘤活性的苦木内酯成分后,又进一步分得一新生物碱和一新苦木内酯,通过理化常数和光谱(UR,IR,~1HNMR,~(13)C NMR)分析,推断其结构分别为4-乙氧甲酰基喹诺-2-酮(4-ethoxyca-

关 键 词:鸦胆子  4-乙氧甲酰基-喹诺-2-酮  鸦胆因
收稿时间:1989-01-11

STUDIES ON THE CHEMICAL CONSTITUENTS OF BRUCEA JAVANICA (L.) MERR
YN Yu and X Li.STUDIES ON THE CHEMICAL CONSTITUENTS OF BRUCEA JAVANICA (L.) MERR[J].Acta Pharmaceutica Sinica,1990,25(5):382-386.
Authors:YN Yu and X Li
Institution:Shenyang College of Pharmacy.
Abstract:An alkaloid and a quassinoid were isolated from the fruit of Brucea javanica (L.) Merr, and were identified as 4-ethoxycarbonyl-2-quinolone (1) and bruceine I (2). Compound 1 was found from natural resource for the first time. The structure of the new compound 2 was elucidated on the basis of spectral data and chemical evidence. Three well known compounds vanillic acid (3), quercetin-3-O-beta-D-galactoside (4), and luteolin-7-O-beta-D-glucoside (5) were also isolated. All of them were first reported to occur in the Brucea genus.
Keywords:4-Ethoxycarbonyl-2-quinolone  Bruceine Ⅰ  Brucea iavanica (L  )Merr
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