化痰通络法改善痰瘀阻络型急性冠脉综合征症状及CRP水平

目的：观察化痰通络法对于改善痰瘀阻络型的急性冠脉综合征患者的临床症状及CRP水平的作用。方法：采用前瞻性对照研究的方法，临床选取中医辨证为痰瘀阻络型的60例急性冠脉综合征患者，随机分为治疗组30。人，对照组30人。两组均给予常规药物治疗，治疗组加以冠心Ⅲ号方治疗。分别于治疗前后检测两组CRP水平，比较治疗前后两组的临床症状改善程度差异及两组CRP水平的差异。结果：①治疗后两组比较，治疗组疗效明显优于对照组，差异有统计学意义（P〈0．05）。②两组主要症状的疗效比较，胸闷痛，气短喘促，舌苔浊腻症状有显著性差异（P〈0．05）。③两组患者经过治疗后CRP数值均能明显下降（P〈0．05）。治疗后治疗组患者CRP水平明显低于对照组患者（P〈0．05）。④随访3个月内心血管事件中，治疗组事件发生率明显低于对照组（P〈0．05）。结论：化痰通络法能提高痰瘀阻络型急性冠脉综合征疗效，改善胸闷痛，气短喘促，舌苔浊腻等，与对照组比较，能更有效降低急性冠脉综合征患者的CRP水平。

The Change of the Level of C-reactive Protein about Improving Symp toms of "Phlegmresolving and Collateral-unblocking Therapy" to the Acute Coronary Syndrome Patients

Objectives：By observing the change of the level of C-reactive protein, we want to observe the effect of improving symptoms of＂ Phlegmresolving and Collateral-unbloeking Therapy＂ to the Acute Coronary Syndrome patients. Methods： We used prospective and comparison study method. In this way 60 cases with Acute Coronary Syndrome was collected. And they were all Phlegm-stasis Blocking Collateral Type by differential diagnosis. All cases were divided into control and treatment group at random, each group were 30 cases. They were treated conventionally, but the treatment group was given Guanxin Ⅲ in addition. C-reactive protein level was detected in two groups before and after treatment. By comparing C-reactive protein level differences of the two groups before and after treatment, We can compare the improving of clinical symptoms between the two groups before and after treatment. Results ： 1. The effect of treatment group was significantly better than the control group before and after treatment. 2. The effect of major symptoms such as dyspnoea, choking sensation in chest, fur of the tongue in two group was significant （ P 〈 0.05 ）. 3. The level of C- reactive was dropped significantly before and after treatment in two groups（ P 〈 O. 05）. 6. In dropping the level of C-reactive, the treatment group was better than the control group（ P 〈 0.05）. 4. During the 3 months regular observations,, the rate of cardiovascular events in treatment group is lower than control group significantly. Conclusion： Phlegm-resolving and Collateral-unblocking Therapy can improve the Acute Coronary Syndrome, such as dyspnoea,choking sensation in chest, fur of the tongue. Moreover, comparing the control group, it can reduce the level of C-reactive of Acute Coronary Syndrome patients significantly.