| 脾原发性血管肉瘤5例临床病理分析 |
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| 引用本文： | 庞有成,于国,任刚,王华,纪宇. 脾原发性血管肉瘤5例临床病理分析[J]. 诊断病理学杂志, 2007, 14(3): 197-198 |
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| 作者姓名： | 庞有成 于国 任刚 王华 纪宇 |
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| 作者单位： | 1. 北京丰台医院桥南部,病理科,北京,100070
2. 解放军总医院,病理科,北京,100853 |
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| 摘 要： | 目的探讨脾原发性血管肉瘤的临床病理学特征、诊断及鉴别诊断。方法主要从临床表现、大体检查、光镜和免疫组化方面进行观察并随访。结果5例中男性3例,女性2例,年龄在44～60岁,平均52岁。肿瘤最大者20cm×18cm×8cm,最小者5cm×3cm×3cm。免疫组化瘤细胞F8、CD34、CD31和vimentin均（＋）。结论脾血管肉瘤罕见,临床缺乏特异性,病理形态多样,诊断困难,免疫组化特异性标记可明确诊断。
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| 关 键 词： | 脾 血管肉瘤 临床病理 免疫组化 |
| 文章编号： | 1007-8096（2007）03-0197-02 |
| 修稿时间： | 2006-12-15 |
Primary angiosarcoma of spleen: a clinicopathologic analysis of 5 cases report and review of literature |
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| PANG You-cheng, YU Guo, REN Gang. Primary angiosarcoma of spleen: a clinicopathologic analysis of 5 cases report and review of literature[J]. Chinese Journal of Diagnostic Pathology, 2007, 14(3): 197-198 |
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| Authors: | PANG You-cheng YU Guo REN Gang |
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| Affiliation: | 1. Department of Pathology, Qiao Nan Division, Beijing Fentai Hospital, Beijing 100070; 2. Department of Pathology, General Hospital of PLA, Beijing 100853, China |
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| Abstract: | Objective To investigate the clinicopathologic features, pathological diagnosis and differential diagnosis of splenic angiosarcoma. Methods 5 cases of splenic angiosarcoma were studied with clinical data analysis, macroscopy, microscopy and immunohistochemical staining. Clinical follow- up was conducted. Results There were 3 males and 2 females with average age of 52 years. Macroscopically, splenic angiosareoma in this study ranged from 5 to 20 cm in diameter. Two cases were multinodular, and three, solitary. Positive rates of immunostaining for CD31, vimentin, CD34 and F8 were 100% respectively. Conclusions Angiosarcoma of the spleen is a rare tumor with pleomorphic histopathological features. It lacks specific manifestations. Immunohistochemical markers can be used for definite diagnosis. |
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| Keywords: | Spleen Angiosarcoma Clinical pathology Immunohistochemistry |
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