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Study on static morphometric parameters for a diagnostic approach of osteoporosis
Authors:M C Voisin  A Kemeny  A M Canalia  Y Pinaudeau
Affiliation:Département de Pathologie, Faculté de Medecine Université Paris- Val-de-Marne, Hôpital Henri Mondor 51, Avenue du Maréchal de Lattre de Tassigny F-94010 Créteil, France;Laboratoire de Biochimie du Tim Con jonctif, GR CNRS No 40, Faculté de Médecine, Université Paris- Val-de-Marne, 8, rue du Général Sarrail F-94010 Créteil, France;Departement de Pathologie, Faculté de Médecine Université Paris- Val-de-Marne, Hôpital Henri Mondor 51, Avenue du Marechal de Lattre de Tassigny F-94010 Créteil, France
Abstract:
The diagnostic value of the morphometric parameters Vv,Sv, dtrab of cancellous bone and relations between them were examined. Iliac bone biopsies of osteoporotic and spasmophilic subjects were studied by means of a Mop 1 semi automatic digitizer tablet joint to a C B M 3032 microprocessor. Both the average Sv and Vv values were significantly different between the two groups. Concordance of Sv values with the radiological diagnosis was closer than Vv ones. The global estimation of mean trabecular thickness is discussed. In conclusion the confrontation of experimental data shows that simple global measure of Sv completes and precise the knowledge of skeleton state.
Keywords:Bone biopsies  osteoporosis  bistomorpbometry  trabecular thickness  surface density
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