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| 去垂体后酪氨酸抗hCG致孕酮生成的作用 | |
| 引用本文： | 王京花 姚兰春. 去垂体后酪氨酸抗hCG致孕酮生成的作用[J]. 哈尔滨医科大学学报, 1989, 23(6): 391-394 |
| 作者姓名： | 王京花 姚兰春 |
| 作者单位： | 哈尔滨医科大学生殖内分泌研究室(王京花，姚兰春，马蒲生)，哈尔滨医科大学生殖内分泌研究室(程治平) |
| 摘 要： | 本实验室曾在离体或整体动物实验证明,酪氨酸有抑制hCG致孕酮生成作用。为了进一步观察酪氨酸的抑制作用不需要垂体参与,我们使用去垂体后24小时的大鼠实验。结果证明,大鼠去垂体后,酪氖酸仍有抑制hCG致孕酮生成的作用。这表明在整体情况下。酪氨酸抑制作用的部位在卵巢,而不需垂体参与。 |
| 关 键 词： | 酷氨酸 孕酮 hCG 垂体 |
Effect of Tyrosine on Production of Progesterone Induced by hCG in Hypophysectomized Rat |
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| Wang Jinghua et al. Effect of Tyrosine on Production of Progesterone Induced by hCG in Hypophysectomized Rat[J]. Journal of Harbin Medical University, 1989, 23(6): 391-394 | |
| Authors: | Wang Jinghua et al |
| Affiliation: | Reproductive Endocrinology Laboratory |
| Abstract: | Tyrosine can significantly inhibit progesterone secretion induced by hCG in the ovary both in vivo and in vitro. From our Previous experiments we tentatively proposed that the effect does not need the Participation of the pituitary. In the present report the inhibitory effect of tyrosine on hCGinduced progesterone production was reexamined in hypophysectomized rats. The results showed that progesterone production could be evoked by hCG in hypophysectomized rats , while 0.9% NaCl had no effect. However, the hCGinduced production of progesterone was significantly blocked by tyrosine in the hypophysectomized rats. It is believed therefore, that tyrosine acts at the ovary level, and the pituitary gland is not essential for the tyrosine inhibitoryeffect to occur. |
| Keywords: | Tyrosine Progesterone Hypophysis hCG |
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